-
Integral proteins
Extends into or through the lipid bilayer and are firmly embedded it it. ( most are transmembrane proteins)
-
Hydrophilic
polar portion water loving
-
hydrophobic
- non polar portion
- water fearing
- 2 long fatty acid chains
-
Transmembrane proteins
- span the entire lipid bilayer and protrude into the cytosol
- includes channels that allow ions to cross the membrane
-
peripheral protein
not as firmly embedded, loosely bount to the membrane by associations
-
glycoprotein
- proteins with an attacthed carbohydrate group at the end of the protein that protrudes into the extracellular fluid
- enables a cell to recognize other cells of same kind or to recognize and respond to dangerous foreign cells
- located mainly on the extracellular surface
-
Antigen
Any material that causes an immune response
-
Fluid mosaic model
- called so because of the presence of proteins that are dispersed in the bilayer
- consists of phospholipids, cholesterol, proteins and carbs
-
what parts of the membrane are hydrophilic vs parts that are hydrophobic
- the fatty acid "tails" are hydrophobic/non polar
- the "head" is hydrophilic/ polar
-
Peripheral proteins
loosely bound to the membrane by associations with integral membrane proteins or phospholipids
-
Integral Proteins
extend into or through the lipid bilayer and are firmly embedded in it
-
Transmembranal Proteins
- Spans the entire lipid bilayer and protrudes into the cytosol
- includes channels that allow ions to cross the membrane
-
Cholesterol
interferes with hydrophobic interactions between phospholipid tails, which may cause crystallization of the bilayer and may decrease fluiditity
-
Functions of membrane proteins
- form ion channels
- act as transporters
- some are enzymes
-
Tight junction
- serves as a barrier
- blood/brain
- stomach
-
Desmosome ( Adherence) Junction
- Specialized in cell to cell adhesion
- provides strength so cells dont tear apart
- heart, uterus, skin
-
Gap junction
- Communication junction allows cells to communicate very quickly
- neurons
-
Active transport
transportation of molecules across a membrane that requires energy
-
Permeable
able to move across a membrane with ease
-
Concentration gradient
unequal distribution of ions
-
diffusion
movement of material from high concentration to low concentration
-
Osmosis
Diffusion of water across a membrane
-
Membrane channel
pathway that allows for movement of material from one end to another
-
Voltage
unequal charge distribution across the membrane
-
Membrane potential
a difference in electrical potential or voltage that appears across the membranes of most cells
-
Electrochemical gradient
the sum of the electrical and chemical gradients acting on an ion or charged molecule
-
Facilitated diffusion
the passive movement of molecules across a membrane by way of a transport protein
-
Functions of the cell membrane
- separates the cell from the extracellular fluid
- contains the organelles of the cell
- allows for some permeability
- movement of ions in or out
-
factors that determine permeablilty of a material
- size of channel
- charge of interior portion of channel
- shape of diffusing molecule
- temperature
- membrane thickness
- lipid solubility
-
Active movement
- requires energy
- moves against concentration gradient
passive moves with gradient
-
Diffusion, Osmosis
Passive transport
-
sodium / potassium pump
active transport
-
sodium potassium pump
- the pump works to reestablish sodium concentrations outside the cell and potassium concentrations inside the cell after an action potential.
- It uses energy to pump 3 na out and to put 2 k in.
-
membrane channel regulation
-
membrane channel structure
-
Endocytosis
Molecules in the extracellular fluid enter the cell through the formation of vesicles called endosomes( from the plasma membrane)
-
Phagocytosis
- cell eating
- cell uses movements of its membrane to form an enclosed phagosome in the cytoplasm
- common in white blood cells for removing foreign particles and bacterial
-
Pinocytosis
- membrane indents and pinch together to enclose the particle
- cell drinking
- non specific process and the contents of the vesicle is extracellular fluid containing dissolved solutes
-
Exocytosis
vesicle inside the cell fuses with the membrane and releases its contents into the extracellular fluid
|
|