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ADT Exam 2
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Thixotropic systems demonstrate a ____ in viscosity with time under constant shear
decrease
Rheopectic materials becomes ___ viscous as the duration of applied force increases
more
pseudoplastic flow
decreased viscocity with shaking
polymer systems
thixotropical flow
viscosity decreases with shear but increases when shearing is stopped
examples of pseudoplastic
ketchup
toothpaste
polymer solutions
examples of rheopectic
cement and drilling mud
thixotropical examples
corn syrup
engine oil
measurement of thixotropy
hysteresis loop
viscometers
Factors affecting thixotropic properties
Temperature
pH
polymer concentration
polymer combination
polymer modification
addition of cations
addition of excipients
mucin
1.5% of fluid
main roll is regulating viscocity
highly glycosylated glycoproteins
acidic pH maintained by
doiderlein's bacillus which produce lactic acid
Lactobacillus produce hydrogen peroxide
Na/H and Cl/HCO
3
exchangers
Factors affecting drg release profile and efficacy of the intravaginal delivery system
microbicide concentration
loading weight
flow rate
pH
speed of rotation
site of application
Author
Rx2013
ID
114936
Card Set
ADT Exam 2
Description
Thixotropic properties
Updated
2011-11-06T22:14:03Z
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