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Bacillus Anthraces
- Antrax (cytosine) -> increases vascular permeablity
- hemorrhage and pulmonary edema
-
Bacillus cereus
- Enterotoxin _> causes excessive loss of water and electrolytes
- diarrhea
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Clostridium Botulinum
- Botulism (8 surgical types; neurotoxins) -> blocks release of Ach at nerve ending
- respiratory paralysis, double vision
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Clostridium Perfringens (1)
- gas gangrene (alpha-txin, a hemolysin) -> breaks down lecithin in cell membranes
- cell and tissue destruction
-
Clostridium perfringens (2)
- Food poisoning (enterotoxin) -> auses excessive loss of water and electrolytes
- diarrhea
-
Clostridium tetani
- tetanus (lockjaw) (neurotoxin) -> inhibitis antagonists of motor neurons of brain; 1 nanogram can kill 2 tons of cells
- violent skeletal muscle spasms, respiratory failure
-
Corynebacterium diphtheria
- diphteria; produced by virus-infected (cytosine) bacteria -> inhibits protein synthesis
- heart damage can cause death weeks after apparent recovery
-
Escherichia coli (1)
- Traverlers diarrhea (enterotoxin) -> causes excessive loss of water and electrolytes
- diarrhea
-
Escherichia coli (2)
- 0157; H7 (enterotoxin) -> hemolytic uremic syndrome
- destroys intestinal lining and causes hemorrhages in kidney
- bleeding and kidney hemorrhage and failure
-
Pseudomonas aeruginosa
- various infections (exotoxin A) -> inibits protein synthesis
- lethal necrotizing lesions
-
Shigella dysenteriae
- bacillary dysentery (enterotoxin) -> cytotoxic effects; as potent as botulinum toxin
- diarrhea, causes paralysis in rabbits from spinal cord hemorrhage and edema
-
Staphylococcus aerus (1)
- food poisoning (enterotoxin) -> stimulates brain center that causes vomitting
- vomitting
-
Staphylococcus aerus (2)
- scaled skin syndrome (exfolatin) -> causes intradermal separation of cells
- redness and sloughing of skin
-
Streptococcus progenies
- scarlet fever (erythrogenic, or red-producing toxin) -> causes vasodilation
- maculopapular (slightly raised, discolored) lesions
-
Vibrio cholerae
- Cholera (enterotoxin) -> causes excessive loss of water (up to 30L/day) and electrolytes
- diarrhea; can kill within hours
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