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Cells that convert from one type of cell to another:
Metaplasia
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Cells that lack normal cellular characteristics and differ in shape and organization with respect to their cells of origin (ultimately determines the malignant potential)
Anaplasia
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Bizarre cell growth resulting in cells that differ in size, shape, or arrangement from other cells of the same type of tissue
Dysplasia
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What are secondary prevention strategies for cancer?
Detection and screenings- mammography, pap test, breast and testicular self exam, skin inspection
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A _____ is a drug that will cause extensive soft tissue damage if it leaks into the tissue
vesicant
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Inflammatory response of the oral tissues that is characterized by mild redness (erythema) and edema, or, if severe- by painful ulcerations, bleeding, and secondary infection
Stomatitis
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What medication is given to prevent formation of uric acid crystals?
Allopurinal
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Which chemo drug is often associated with peripheral neuropathies?
Vincristine
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What is the leading cause of death in oncology patients?
INFECTION
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How do we assess thrombocytopenia?
DECREASED PLATELET COUNT
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What is the patient at risk for who has thrombocytopenia?
Trauma, bleeding
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The continued uncontrolled release of ADH antidiuretic hormone produced by tumor cells leads to increased water toxicity- _________.
hyponatremia (Na levels < 120 Meq/L)
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Which term refers to cells that lack normal cellular characteristics and differ in shape and organization with respect to their cells of origin?
Anaplasia
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According to the TNM classification system, T0 means there is:
no evidence of primary tumor
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According to the TNM classification system, M0 means there is:
no distant metastasis
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According to the TNM classification system, M1 means tehre is:
Distant metastasis
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What does TNM stand for?
- T= primary tumor
- N= lymph node involvement
- M= metastasis
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During which stage of cellular carciogenesis do cellular changes exhibit increased malignant behavior?
- Progression
- The third stage of carciogenesis in which cells show a propensity to invade adjacent tissues and metastasize.
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____ is a decrease in neutrophils
Granulocytopenia
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______ is a decrease in the number of platelets
Thrombocytopenia
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A benign tumor of the blood vessels is a:
hemangioma
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Chemotherapeutic agents have which effect associated with the renal system?
increased uric acid secretion
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Following a BMT, the patient should be monitored for at least:
3 months
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What is the treatment for acute DIC?
Recieve a blood transfusion
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Which DIC category is obsevable symptoms such as easy bruising and prolonged bleeding from venipuncture sites?
Chronic DIC
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What is secondary prevention of cancer?
detection and screenings (mammograms, pap test, BSE, TSE, skin inspection)
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Grading of a malignancy; undifferentiated, more aggressive and less responive to treatments would be a grade ___
4
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Grading of malignancy; well differentiated, closely resemble tissue of origin would be a grade ___
1
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_______: determines size of the tumor and presence of metatastasis
Staging
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_______: increase in cell size
hypertrophy
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______: increase in number of cells
hyperplasia
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_____: does not follow any kind of physiologic demand
Neoplasia
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_____: bizzare cell growth pattern
dysplasia
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_____: does not have normal cell characteristics
Anaplasia
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______: cells convert to another type of cell
metaplasia
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During the ____ phase of the cell cycle, the cell doubles its DNA
S
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During the ___ phase of the cell cycle, the cell divides into two cells
M
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_______ cells: rate of growth is not normal but still follow normal cell growth patterns
Benign
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______: process of transforming normal cells into malignant cells
Carcinogenesis
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______: where the cells normal structure is altered by either external or internal agents
Initiation
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_______: (where the cells become mutated) repeated exposure to promoting agents (carcinogens) causes the expression of abnormal or mutant genetics information
Promotion
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______: where the cells become malignant (the altered cells exhibit increased malignant behavior)
Progression
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______ spread: dissemination of malignant cells via the bloodstream and is directly related to the vascularity of the tumor
hematogenous
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_______: the growth of new capillaries from the host tissue by the release of growth factors and enzymes such as VEGF
Angiogenesis
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Radiation may cause radiodermatitis.... what do you need to monitor for?
- Monitor for moist desquamation
- - Weeping of the skin due to loss of upper layer of the skin
- - Apply antibiotic ointment or steroid cream as prescribed
- - Expose site to air
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How should the patient be postioned when receiving radiation?
less than 45 degrees and must be log roleed to prevent implant from dislodging
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______ surgery is performed to relieve complications of cancer
Palliative
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The nurse is monitoring a client for signs and symptoms related to superior vena cava syndrome. What is an early sign of this oncological emergency?
Periorbital edema
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