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pre-diabetic blood sugar
100-125
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a1c
- >6.5%
- diabetic goal: <7%
- normal goal: <6%
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LDL
- optimal: <100
- near optimal: 100-129
- borderline high: 130-159
- high: 160-189
- very high: >190
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Total Cholesterol
- optimal: <200
- borderline high: 200-239
- high: >240
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TG
- normal: <150
- borderline high: 150-199
- high: 200-499
- very high: >500
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BMI
- underweight: <18.5
- normal: 18.5-24.9
- overweight: 25-29.9
- obese I: 30-34.9
- obese II: 35-39.9
- extreme obese III: >40
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Na
- 135-147 mEq/L
- sxs hyper: AMS, decreased urine output, lethargy, seizures, thirst
sxs hypo: AMS, seizures, disorientation, muscle cramps
Trileptal and tegretol decrease Na
indicates fluid balance
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K
3.5-5mEq/L
sxs hyper: cardiac arrhythmia, bradycardia, hypotension
sxs of hypo: cardiac arrhythmia, muscle weakness/cramp, fatigue
ACEI/ARB increase K, diuretics decrease K
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Mg
1.5-2.3 mEq/L
sxs hyper: cardiac arrhythmias, sedation, lethargy, muscle weakness
sxs hypo: cardiac arrhythmias, tetany, muscle irritability, N/V
renally excreted
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Ca
8.6-10.2 mg/dL
sxs hyper: weakness, anorexia, constipation, N/V
sxs hypo: muscle cramps, tingling fingers, tetany, seizures
important in neuromuscular fxn, bone formation, need to correct for low albumin
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BUN/SCr
BUN: 8-18 mg/dL
SCr: 0.6-1.2 mg/dL
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Kidney dysfunction
- Stage I: kidney dmg w/ normal gfr
- ClCr >90
- Stage II: dmg with mild reduction in GFR
- ClCr 60-80
- Stage III: dmg with moderate reduction in GFR
- ClCr 30-59
- Stage IV: dmg with severe reduction in GFR
- ClCr 15-29
- Stave V: Kidney Failure
- ClCr <15
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AST (Aspartate aminotransferase)
ALT (Alanine aminotransferase)
- AST: 0-40 IU/L
- Found primarily in heart/liver, increased in MI and acute hepatic necrosis
- ALT: 0-40 IU/L
- Found primarily in liver, more sensitive to hepatic dmg than AST
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AlkPhos (alkaline phosphatase)
30-120 IU/L
Increased in hepatitis, liver diease, pancreatitis, bone disorders
- Use 2ndary GGT test
- high AlkPhos+GGT = liver disease
- high AlkPhos + Normal GGT = bone disorder
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Albumin
4-6 g/dL
decreased: overhydration, malnutrition, cancer, severe burns, pregnancy, cirrhosis, hepatitis, liver failure
hypoalbuminemia: leads to edema and ascites
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Amylase
Lipase (more specific)
amylase: 30-100 IU/L
Lipase: 0-160 IU/dL
high in pancreatic injury, acute pacreatitis, obstruction of pancreatic duct by gallstone/tumor
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TSH/T3/T4
TSH: 0.3-5 uIU/L
- T4 5-12 ug/dL
- Free T4 0.8-2.2 ng/dL
T3: 75-200 ng/dL
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RBC
M: 4.3-5.9 x 10^6/mm^3
F: 3.5-5 x 10^6/mm^3
use Hgb and Hct to monitor qualitative changes in RBCs
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Hgb/Hct
- Hgb:
- M: 14-18 g/dL
- F: 12-16 g/dL
increased in dehydration
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MCV (mean cell volume)
75-100 fL/cell
describes cell size (MCV = Hct/RBC)
- if H/H are low:
- MCV low: microcytic anemia, iron deficiency
- MCV high: macrocytic anemia, folic acid deficiency
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Platelets
150-400 x 10^3/mm^3
- high: thrombosis/clot formation
- low: excessive bleeding (can be drug induced, heparin, bactrim, ASA)
targeted by Plavix (anticoag)
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WBC
3.5-10 x 10^3/mm^3
high: leukocytosis from infxn, sepsis, leukemia
low Leukopenia, drug induced or disease, at risk for infxn
"left shift": increase in bands (immature WBC to fight off an infxn)
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ANC
Neutropenia: <2000
ANC <1000 at risk for infxn
Agranulocytosis: <500 (high risk of infxn)
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Phenytoin
10-20 mcg/mL
- If low albumin, adjust levels
- adjusted PHT = PHT/(0.2*alb + 0.1)
toxicity: slurred speech, ataxia, confusion, nausea, nystagmus
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Vancomycin
10-20mcg/mL
toxicity: ototoxicity, nephrotoxicity, vertigo, dizziness, tinnitus
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