Pharm E2/1/Renal

  1. Within the glomerulus, what structures allow small molecules & water to pass?
  2. Within the glomerulus, what structures regulate filtration via relaxation/constriction to alter SA
    Mesengial Cells
  3. What induces constriction/contraction of mesengial cells?
    • Sympathetic Innervation
    • Angiotensin II
  4. Where is 60-70% of Na and H2O reabsorbed?
    Proximal Convoluted Tubule
  5. What is permeable within the Descending Loop of Henle? Ascending Loop?
    • Descending= H2O
    • Ascending= Na & Cl
  6. What two drugs prolong Penn?
    • Probenicide
    • Sulphinpyrazone
  7. What Drugs act on the Proximal Tubule?
    • Carboanhydrase Inhibitors:
    • Acetazolamine
  8. What Drugs act on the Loop of Henle?
    • Loop Diuretics:
    • Furosemide
    • Bumetadine
    • Torasemide
  9. Which Drugs act on the Distal Convoluted Tubule?
    • Thiazide Diuretics:
    • Chlorothizide
    • Hydrochlorothiazide
  10. What Drugs act on the Distal Convoluted Tubule?
    • K Sparing Diuretics:
    • Amilorida
    • Triamterene
    • Spironolactone
  11. Which class is a mild diurectic and used to Tx glaucoma?
    Carboanhydrase Inhib
  12. Which drug type decreases the secretion of Uric Acid?
    Loop Diuretics
  13. Which Class is the most powerful of all diruectics?
    Loop Diuretics
  14. Which durg classes => Metabolic Acidosis?
    Carboanhydrase Inhibitors
  15. Which drugs decreases Na reabsorption and H2O Reabsorption?
    Osmotic Diuretics
  16. Which drug class is used to Tx Hypokalemia & edema/Ascites?
    Distal/K Sparing Diuretics
  17. Which Drugs Classes => Metabolic Alkalosis?
    • Loop Diuretics
    • Thiazide Diuretics
  18. Which drugs => Hypokalemia?
    Loop Diruetics
  19. Which durg may reduce bone loss?
  20. Which drug can cause hyperglycemia?
  21. Thiazides are used to Tx:
    • Diabetes Insip.
    • Mild HF
    • Hypertension (Volume and Dilation)
  22. _______ will not be absorbed form horse urine
    Weak Acids
  23. Amiloride is a _____ diuretic
    K Sparing
  24. Action of Furosimide
  25. Two vasodilators that affect renal perfusion:
    • Dopamine
    • Prostaglandin
  26. Spironolactone
  27. Thiazide Diuretics acts on….
    The Distal Convoluted Tubule
  28. How & Where are Weak Acids excreted?
    • Active Transporters in the
    • Proximal Tubles
  29. Which Drugs increase renal perfusion? Which are Contraindicated w/ NSAIDS?
    • Eicoasnoids (<- contraindicated)
    • Thiazides
Card Set
Pharm E2/1/Renal
Pharm E2/1/Renal