All the following are complement-controlling proteins excepts:
a. C1 (INH)
b. Factor I.
c. Factor H.
d. C3.
Various cell types express surface membrane glycoproteins that react with one or more of the fragments of_________produced during complement activation and degradaton.
C1
all the following result from complement activation except:
a. Decreased cell susceptibility to phagocytosis.
b. Blood vessel dilation and increased vascular permeability.
c. Production of inflammatory mediators.
d. Cytolysis or hemolysis.
Complete the following activation sequence of the classic complement pathway:
which complement component is present in the greatest quantity in plasma?
3
Arrange the three stages of the classic complement pathways in their corrct sequence.
- Recognition
-Enzymatic activation
-Membrane attack
Fixation of the C1 complement component is related to each of the following factors except:
a. Molecular weight of the antibody.
b. The presence of IgM antibody.
c. The presence of most IgG subclasses.
d. Spatial constraints.
At which stage does the complement system reach its full amplitude?
C3
Which of the following is not a component of the membrane attack complex?
C3b
The final steps (c8 and C9) in complement activation lead to :
Cell lysis.
Select the appropriate pathway response:
____Activated by antigen-antibody complexes
_____Generates a C3 convertase
_____Activated by microbial and mammalian cell surfaces
______Terminates in a membrane attack complex
a. Classic pathway
b. Alternative pathway
c. Both a and b
The alternate complement pathway is/can be:
a. Initiated by the formation of antigen-antibody reactions.
b. Predominantly a non-antibody-initiated pathway
c. Activated by factors such as endotoxins.
d. Both b and c
which of the following conditions can be associated with hypercomplementemia?