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Hematological Cell Identification
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The Mitochondria is what to the cell?
-powerhouse of cell for energy production
-respiration
What is Lysosome?
Hydrolytic enzymes to destroy bacteria
White Blood cells (leukocytes) defend against..
-foreign substances
-microorganisms
-parasites
-infection
What are Platelets(thrombocytes) ?
-cytoplasmic fragments of megakaryocytes
-stops bleeding
What is the primary site of cell production?
Bone marrow
Bone Marrow provides what?
best source of study for production and maturation of cells
Diagnostic cells may only be present?
marrow
Bone marrow is examined by who?
by the Pathologist
What happens during the second week of Fetal Development?
Primitive RBC's
In what month does granulocytes and megakaryocytes happen during the fetal development?
The second month
What happens in the fourth and fifth month of fetal development?
4th month lymphocytes , 5th month monocytes
What does a immature nucleus looks like?
-large, almost occupying the entire cell
-N/C ratio is high
-usually round to oval
Describe an immature nucleus
chromatin fine and delicate
stains
reddish
purple
usually with 1 or more nucleoli
Name the cell
Band
The nucleus in a band cell is what shape?
rod or band
*indentation greater than half the width of round nucleus
chromatin coarser and clumped
What is the ratio of nucleus to cytoplasm on a band?
1:1
What is the most frequently occuring cells in peripheral blood?
Neutrophil
In the regulation of Neutrophil cells what is released first?
segmented cells released first before the bands
What percentage of bands released in circulation?
only a small percentage
Wh
What is Diapedesis?
Neutrophils move into tissues thru narrow junctions between endothelial cells of blood vessels
Eosinophil
What is the size of an Eosinophil?
10-16 um
Describe the nucleus on a Eosinophil?
usually two lobes
coarse & clumped chromatin
Describe the cytoplasm on an Eosinophil?
Bright
reddish
-
orange
specific granules
granules distinct & uniform size
What happens in IgE hypersensitivity reaction(basophil)?
binds to surface receptors
*react w/ specific antigens
What happens when degranulation occurs(basophil)?
Enzymes released in area
contains histamine & heparin
What is the primary Lymphopoietic organs?
Bone marrow & thymus
What is the secondary lymphopoietic organs consist of?
Lymph nodes, spleen, tonsils
What is the second most frequently occuring WBC in peripheral blood?
Lymphocytes
Where do lymphocytes originate from?
from CFU-L in lymphopoietic organs
Which lymphocyte establish direct contact w/ foreign cell?
T Lymphocyte
The T lymphocyte inhibits and kills what?
inhibits growth of foreign cell
kills foreign cell
T lymphocytes are involved in what?
tumor suppresion
graft rejection
What is another name for plasma cells?
Plasmacytes
End stage of B lymph maturation is what cell?
Plasmacytes
Plasmacytes originates from what?
antigenic stimulation of mature B lymphocytes
B lymph transform into what?
plasmablast
Plasmacytes are what type of producing cells?
Antibody
A Mature monocyte's cytoplasm is abundant w/??
pseudopodia
A mature monocyte's cytoplasm color and is?
-pale
blue
-
gray
-ground glass appearance
-fine pale red dust-like granules
-vacuoles may be present
Monocytes exhibits what?
-chemotaxis
-
necrotaxis(attraction to dead or dying cells)
-necrophagocytosis
How long does monocytes spend in peripherial blood?
approximately 14 hours
-enters tissue
-converts into macrophage
Hemoglobin A(HbA) is composed of what chains?
2 alpha
2 other chain
*2 other chain determine the type of Hgb
What is the percentage of hemoglobin in adults for HbA?
95%-97%
What is Hemoglobin F also know as?
Fetal Hemoglobin
Hemoglobin F is composed what chains?
2 alpha chains
2 gamma chains
What is the percentage of adult hemoglobin F?
1%-2%
Platelets are fragments of what?
megakaryocytes cytoplasm
Megakaryocytes yields about how many platelets?
2000 to 4000
Author
babybless88
ID
11257
Card Set
Hematological Cell Identification
Description
Test questions
Updated
2010-03-19T19:19:04Z
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