Volume 1 Chapter 9 Pt. 2

Drug that best demonstrates the class's common properties and illustrates its particular characteristics

Central Nervous System- Brain and Spinal Cord

• Peripheral Nervous System- All nervous tissue outside of CNS
• Autonomic Nervous System- Controls involuntary "automatic" functions
• Sympathetic- "Fight or Flight"- Tends to speed things up
• Parasympathetic- "Feed and Breed"- Tends to slow things and inhibit
• Somatic Nervous System- Controls voluntary motor functions

Medication that relieves the sensation of pain

The abscence of the sensation of pain

The abscensce of all sensations

Agent that enhances the effects of other drugs

Medication that induces a loss of sensation to touch or pain

Anesthesia that combines decreased sensation of pain with amnesia while the patient remains conscious

State of decreased anxiety and inhibitions

Instigation of sleep

Gamma-aminobutyric acid. Chief inhibitory neurotransmitter in the CNS

Increase the GABA receptor-cloride ion channel complexes' potential for binding with GABA. Antagonist is Flumazenil

• Partial Seizures: Phenytoin (Dilantin)
• Carbamazepine
• Grand Mal: Carbamazepine
• Phenytoin
• Phenobarbital

• Absence: Valproic Acid
• Ethosuximide

Drug used to treat mental dysfunction

Common side effects of antipsychotic medications including muscule tremors

Antipsychotic effecting the nerve.

• -Ticyclic Anti-depressants (TCA)
• -Selective Serotonin Reuptake Inhibitors (SSRIs)
• -Monoamine Oxidase Inhibitors (MAOIs)

The part of the nervous system that controls involuntary functions

Groups of autonomic nerve cells located outside the centra nervous system

Nerve fibers that extend from the central nervous system to the autonomic ganglia

Nerve fibers that extend from the autonomic ganglia to the target tissues

Space between nerve cells

Specialized synapse between a nerve cell and the organ or tissue it innervates

Chamical messenger that conduct a nervous impulse across a synapse

Nerve cell

Pertaining to the neurotransmitter acetylcholine

Pertaining to the neurotransmitter norepinepherine

• -III
• -VII
• -IX
• -X

• -Pupillary Constriction
• -Secretion by Digestive Glands
• -Reduction in heart rate and cardiac contractile force
• -Bronchoconstriction
• -Increase smooth muscle activity along the digestive tract

Drug or other substance that causes effects like those of the parasympathetic nervous system. AKA Cholinergic

Drug or other substance that blocks or inhibits the actions of the parasympathetic nervous system. AKA Anticholinergic

• Nicotinic (Sympathetic and Parasympathetic):
• -Found at neuromuscular junction of skeletal muscles only
• -Found on postganglionic parasympathetic nerves
• -Found on many neurons in the brain
• -Nicotine is an agonist
• -Curare is an antagonist

• Muscarinic (Parasympathetic):
• -Found at the neuromuscular junction of smooth and cardiac muscle
• -Found on postglanionic sympathetic nerves
• -Found on glands
• -Muscarine is an agonist
• -Atropine is an antagonist

• Salivation
• Lacrimation
• Urination
• Defecation
• Gastric motility
• Emesis

• -Muscarinic
• -Nicotinic
• -Nicotinic n (Neuron)
• -Nicotinic m (Muscle)

• -Hot as hell
• -Blind as a bat
• -Dry as a bone
• -Red as a beet
• -Mad as a hatter

• -Stimulation of secretion by sweat glands
• -Constriction of blood vessels in the skin
• -Increase in blood flow to skeletal muscles
• -Increase in the heart rate and force of cardiac contractions
• -Bronchodilation
• -Stimulation of energy production

• -Adrenergic
• Alpha1:
• Vasoconstriction, metabolisim stimulation

Alpha2: Regulator of norepinepherine

• Beta1: Increased heart rate (chronotropic)
• Increased cardiac contractile force (inotropic)
• Increased cardiac automaticity and conduction (dromotropic)

Beta2: Vasodilation, Bronchodilation

-Dopaminergic: Vasodilation

Drug or other sybstance that causes effects like those of the sympathetic nervous system. AKA Adrenergic

Drug or other substance that blocks the actions of the sympathetic nervous system. AKA Antiadrenergic

Drug used to treat and prevent abnormal cardiac rhythms

Vaughn-Williams and Singh Classification System

• I: Na+ Channel Blockers
• 1A (i.e procainamide, quinidine)
• 1B (i.e Lidocaine, phenytoin)
• 1C (i.e Flecainide, propafenone)

II: Beta-blockers (i.e Propranolol, acebutolol)

III: K+ Channel blockers (i.e Bretylium, amiodarone)

IV: Ca++ Channel blockers (i.e Verapamil, diltiazem)

V: Miscellaneous (i.e Adenosine, digoxin)

Drug used to reduce the circulating blood volume by increasing the amount of urine

The stoppage of bleeding

Drug that decreases the formation of platelet plugs

Drug that interrupts the clotting cascade

Drug that acts directly on thrombi to break them down. AKA Thrombolytic

Drug used to treat high blood cholesterol

Mediator released from mast cells upon contact with allergens

An endogenous substance that affects a wide variety of organ systems

Medication that arrests the effects of histamine by blocking its receptors

Medication that suppressed the stimulus to cough in the central nervous system

Medication intended to increase the productivity of cough

Medication intended to make mucous more watery

Alkalotic compund used to increase the gastric environment's pH

• -Bulk-forming
• -Stimulant
• -Osmotic
• -Surfactant

Medication used to decresease stool's firmness and increase its water content

Substance that decreases surface tension

Medication used to prevent vomitting

Substance that decreases the level of glucose in the blood

Substance that increases blood glucose levels

Drug used to treat cancer

Agent that kills or decreases the growth of bacteria

Disease-causing organism

The body's ability to respond to the prescnce of a pathogen

Solution containing whole antibodies for specific pathogens

Solution containing a modified pathogen that does not actually cause disease but still stimulates the development of antibodies specific to it