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Path Pancreas
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Ectopic Pancreatic tissue could be present in what locations?
ileum
duodenum
jejunum
stomach
meckels diverticulum
What is the basic pathology of acute pancreatitis?
edema
fat necrosis
saponification
What are the causes of acute pancreatitis?
GET SMASHED
Gallstones
Ethanol
Trauma
Scorpion Sting
Mumps
Autoimmune
Steroids
Hypercalcemia/hyperlipidemia
ERCP-endoscopic retrograde cholangiopancreatography
Drugs:sulfa
Risk factor for pancreatic adenocarcinoma?
smoking
pancreatitis---etoh induced
Hep B antigen is associated with what vasculitis?
Poly arteritis nodosa
3 Infectious causes of Acute Pancreatitis?
mumps
Coxsackie
Mycoplasma Pneumoniae
What is the relationship between the calcium level in blood and pancreatitis?
hypercalcemia--activate autolytic enzymes which leads to fat necrosis which consumes calium leading to HYPOCALCEMIA
What is a bad prognosis sign for acute pancreatitis?
Hypocalcemia
Trosussae Syndrome?
migratory thrombophlebitis
Procoagulopathic state bc of Pancreatic Adenocarcinoma
Courvoisier's sign?
obstructive jaundice with palpapble gallbladder
Hemorrhagic pancreatitis can lead to what severe complication?
DIC
Activation of what enzyme triggers autodigestion of pancreas in acute pancreatitis?
Trypsinogen
What marker is more specific for acute pancreatits?
Lipase appears later but more specific
Amylase appears early
How is ARDS developed from Acute Pancreatitis?
acture pancreatits-->shock--->ARDS bc of increased vessel permeability
What are the differentials for acute abdomen?
perforated peptic ulcer
cholangitis
cholecystitis
perforated diverticulitis
What is the difference between acute and chronic pancreatitis?
chronic is just like + fibrosis
CYst?
dilated fluid cavity covered by epithelium
Pseudocyst?
dilated fluid filled cavity lined by fibrotic tissue
What syndrome gives pancreatic/acini cysts?
Von Hippel Disease
When do Pancreatic Pseudocysts form?
after an acute case of pancreatitis
WHich pancreatic cystoadenomas are benign?
Serous cystoadenoma
What is the Oncogene mutation associated with Pancreatic adenocarcinoma?
K-Ras
but also
p53
p16
SMAD4
Pancreatic cancer in the head or neck of pancreas would present how?
Pruritis, jaundice, pale stools, dark urine, steatorrhea, Fat soluble vitamin deficiency
Whats responsible for desmoplasia?
body's immune response to neoplasm
What kind of neoplasm is pancreatic cancer?
ductal carcinoadenoma
Two markers in Pancreatic adenocarcinoma?
CEA
CA-19-9
CA12-5
CA19-9?
Ca12-5--ovarian
CA19-9-pancreatic
Author
pszurnicki
ID
111826
Card Set
Path Pancreas
Description
Path Pancreas
Updated
2011-10-24T21:32:37Z
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