Pathology Viral Carcinogenesis

HPV
- integrated into host cell genome in cancer
- early viral gene products: E6 binds p53, E7 binds RB
- Squamous cell carcinoma of cervix/anogenital, oral and laryngeal cancer
Epstein-Barr
- Enters B cells via CD21
- latent membrane protein-1 (LMP-1) mimicks CD40
- Burkitt's lymphoma, B-cell lymphoma, Hodgkins's lymphoma, nasopharyngeal carcinomas
Hep V
- Liver CA
- Probably dev through insertional mutagenesis
Human T-Cell Leukemia Virus Type 1
- topism for CD4+ T Cells
- Long latent period
H. Pylori
- bacterium, not virus
- gastric carcinomas, lymphomas

Author

jlolson83

110673

Card Set

Pathology Viral Carcinogenesis

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Updated

2011-10-20T22:06:34Z

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