p chem t4

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What is unique to the mucosal cells?

The ability to reutilize the glycerol in the monoglyceride acylation pathway.
What is the major pathway of triglyceride resynthesis?

Monoglyceride acylation pathway
When is the scavenger pathway of mucosal cells mostly used?

in between meals
Only antigenic lipid known

cardiolipin
Glycerophospholipids
- Phosphatidylcholine (lecithin)
- Phosphatidylserine
- Phosphatidylethanolamine (cephalin)
- Phosphatidylinositol
- Plamalogens
- Cardiolipin
Phospholipid functions (to name a few)
- building blocks of membranes.
- components of lipoproteins. contribute constituents (DAG and IP3) to intracellular signal transduction pathways, and to eicosanoid biosynthesis. Play a role in blood coagulation (plasmalogen-PAF). Functional elements of bile (lecithin) and lung surfactant (DPPC).
Cephalin methylates with what to what?

with 3SAM to hepatic lecithin (phosphatidylcholine)
Important SAM methylations

Each methyl group of choline and carnitine. The methyl in epinephrine. Methyls in catecholamine degradation products (catalyzed by COMT). The methyl for modifying purine and pyrimidine bases in DNA and RNA. Methyl for the 5' cap of eukaryotic messenger RNA.
Structure of cardiolipin

Glycerol holding two phosphatidic acid residues together.
Where is cardiolipin found?

Bacterial membranes and inner mitochondrial membranes.
Pulmonary surfactant
- Made up of DPPC (dipalmitoylphosphatidylcholine).
- Decreases the surface tension of alveolar membranes, thus helping to keep alveoli open for gas exchange.

Author

Anonymous

110221

Card Set

p chem t4

Description

physiological chemistry t4

Updated

2011-10-19T15:45:16Z

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