Path T3 tricks.txt

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What activates NK-cells for tumor killing?

IL-2
How do Tumor cells bind to new ECM?
- Laminin
- Integrins w/ reverse polarity
What makes up a teratoma?
- Ectoderm
- Mesoderm
- Endoderm
- *** hair, teeth, skin and other cells all present in same tumor
What cell transducer can activate RAS by becoming inactivated?

NF-1 b/c it normally forms a GTPase to hydrolyze GTP-GDP
Diff b/t grading and staging tumors?
- Grading: differentiation of cells
- Staging: metasteses of cells
Which test is best for malignancy? Why?

Southern blot b/c it picks up the best monoclonality of B/T cells
Fastest decreasing cncer in developing countries?

Gastric adenocarcinoma
What is the first general metasteses site?

Lymph nodes
T/F pulmonary sarcomas are not related to smoking?

True
What is the Rate limiting step in tumor cell differentiation?

Telomerase shortening
What type of cancer is most common in immunodeficiecy cases?

Lymphoma
What is a leiomyoma and what is its origin?
- Smooth muscle cell tumor
- origin: mesenchymal cells
Main cytokine responsible for cachexia?

TNF-alpha
Name the 2 neuroectodermal neoplasma?
- Nevus
- Malignant Melanoma
name the seven neoplasms that are always malignant?
- Hepatoma
- Melanoma
- Multiple myeloma
- Mesothelioma
- Lymphoma
- Glioma
- Seminoma
name the 5 cardiac neoplasms?
- Myxoma
- Rhabdomyoma
- Papillary fibroelastoma
- Lipoma
- Angiosarcoma
Name the 5 common pediatric neoplasms
- Hamangioma
- Port-wine-stain
- Lymphangioma
- Hygroma
- Teratoma
Largest tumor compatible with life?

1kg (10 doublings of 1g tumor)
Why is a Hemangioma a special case of a benign neoplasm?

It is the only un-encapsulated benign neoplasm
Two neoplasms that do not metastasize?
- Glioma
- BCC
What neoplasms participate in Hematologic spread?

Sarcomas

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kepling

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Path T3 tricks.txt

Description

Path T3 tricks

Updated

2011-10-19T20:12:12Z