Biochemistry Exam III

  1. What are the inhibitors and activators of Fructose-6-Phosphate going to Fructose-1,6-Phosphate
    • Phosphofructokinase
    • Stimulating Glycolysis
    • + Fructose-2,6-Phosphate
    • + AMP
    • - Citrate
    • - H+
  2. What are the inhibitors and activators of Fructose-1,6-Phosphate going to Fructose-6-Phosphate?
    • Fructose-1,6-Bisphosphatase
    • Stimulating glyconeogenesis
    • - Fructose-2,6-Phosphate
    • + ATP
    • + Citrate
  3. PKA is activated by:
    Glucagon, low blood glucose levels
  4. What activates FBPase2?
  5. What happens when FBPase is activated?
    • Glycolysis is inhibited
    • Gluconeogenesis stimulated
  6. What activates PFK2?
    Phosphoprotein phosphate
  7. What happens when PFK2 is activated?
    • Glycolysis stimulated
    • Gluconeogensis inhibited
  8. What are the enzymes involved in pyruvate dehydrogenase?
    • Pyruvate dehydrogenase component (TPP)
    • Dihydrolipoyl transacteylase (Lipoic Acid)
    • Dihydrolipoyl dehydrogenase form (FAD)
  9. What does pyruvate bind to in PDH?
    Binds to TPP and kicks of an CO2 to form TDP-OH-CH3
  10. When the acetyl group is bound to TDP where does it goes next?
    • Breaks the disulfide bond in Lipoic acid to form
    • SH
    • S-C=O,-CH3
  11. What is the next step in PDH when the acetyl group is bound to lipoic acid?
    CoA-SH steels the Acetyl group to make Acetyl CoA
  12. After the acetyl group is stolen from Lipoic Acid what is the next step in PDH?
    • The disulfide bound needs to be oxidized to be regenerated which is by E3's FAD
    • Then NAD+ oxidizes FADH2 to FAD+ to reset everything in the enzyme
  13. What are the enzymes of the inner mitochondria?
    • Electron Carriers (Complexes I-IV)
    • ATP synthase
    • Membrane transporter
  14. What are the enzymes of the mitochondrial matrix?
    • Citric Acid cycle enzymes
    • Beta oxidation enzymes
    • Pyruvate Dehydrogenase
  15. What are the enzymes of the outer mitochondria membrane?
    • Acyl CoA synthetase
    • Glycerolphosphate acyl transfrerase
Card Set
Biochemistry Exam III
Glycolysis, Glyconeogenesis