Hypothalamus - Pituitary Drugs

  1. Mecasermin
    Tx?
    A/E?
    MOA?
    • Mecasermin (rIGF-1; TARGET TISSUE)
    • Tx: Laron syndrome (mutated GH-R or Ab to GH-R)
    • A/E:Hypoglycemia (administor W/snack)
    • MOA:give W/RIGF BP-3 clasts longer)
    • -short statue due IGF-I deficiency w/high GH;IGF-1
  2. Sermorelin
    MOA?
    TX?
    • MOA:GHRF
    • TX:Diagnostic,GH def, weight loss in AIDS,lack of GHRH/F
  3. Octreotide
    TX?
    A/E?
    ADMIN?
    • TX:GH overactivity-acromegaly
    • -supress ectopic hormone production by tumors
    • -45x more potent than somatostatin
    • Admin SC(3x/day),IM(1x/mo)
    • A/E: GI side effects;Vit B12 def.conevery tissue responsive somatostatin
Author
catitasilva
ID
109323
Card Set
Hypothalamus - Pituitary Drugs
Description
hypothalamus pituitary drugs
Updated