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A reaction in which NAD+ or NADP+ is formed from reagent NADH or NADPH is ______________ and my be measured by a (an) __________________ in absorbance at 340 nm.
Oxidation: Decrease
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During 3 glucose tests an hour apart on a patient, capillary blood is substituted for venous blood for one of the timed samples.
What results would you expect for the sample, as compared to results expected for venous blood drawn at the same time?
Capillary blood will yield higher results than venous blood
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The major non-glucose-reducing substance present in serum is:
Ascorbic acid
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Which of the following methods for glucose, results in the formation of NADPH for measurement?
Hexokinase
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The formation of glucose from compounds like fatty acids, glycerol, and amino acids is called:
Gluconeogenesis
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The _______________ form of glucose is responsible for its reducing properties
Enol
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The reference method for glucose determination is:
Hexokinas
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In the Beckman Analyzer for glucose, H2O2 is consumed in side reactions by:
Catalase and ethyl alcohol
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A serum specimen for glucose measurement was allowed to stand unseparated on the clot for 6 hours at room temperature before testing. If the original glucose concentration was 200 mg/dL, what approximate results would be expected after 3 hours?
160 mg/dL
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b-glucose +O2 ---- ? ----> D-glucono-d-lactone + H2O2
Glucose oxidase
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The preferred collection tube for preservation of glucose is:
Sodium fluoride
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The following glucose tolerance test results are indicative of what state? Glucose values as assayed by glucose oxidase method are fasting, 130 mg/dL; 60 minuets, 225 mg/dL; and 120 minuets, 205 mg/dL.
Diabetes
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Type I diabetes mellitus may be described by all of the following Except:
Adult- onset type
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Insulin maybe described by all of the following Except:
Active in its C-peptide form
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Which of the following statments maybe associated with the activity of insulin?
Stimulates glycogenesis in the liver
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The glucose value of a NORMAL 2-hour post-prandial serum specimen, as compared to the reference range for a fasting serum glucose, should be:
Approximately the same as the normal fasting glucose level
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Laboratory tests are performed on a post-menopausal, 57- year-old woman as part of an annual physical examination. The patient's 2- hour post- prandial glucose is 220 mg/dL and serum insulin is 15 mU/ml (normal= 6-26). Based on this information, the patient would be classified as:
Non- insulin- dependent diabetes mellitus (NIDDM)
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Which of the following inhibits glycolysis and glucose uptake by muscle cells and causes a rise in blood glucose concentration?
Growth hormone
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A diabetic patient is prescribed a daily regiment of insulin. Which of the following lab procedures would be of most value in determining the degree of glucose control over a 2-month peroid?
Glycated hemoglobin
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Glycation of glomerular basement membranes and capillaries is the main nephropathic effect from:
Diabetes mellitus
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