Mechanisms Eicosanoids

What are the actions of Prostaglandins (PGE2)?
- Vasodilation
- Potentiate edema
- Induces fever
- Causes pain
What are the actions of Prostacyclins (PGI2)?
- Vasodilation
- Inhibits platelet aggregation
- Balances with Thromboxanes
Where is the primary site of synthesis of Prostaglandins (PGE2)?

Widely distributed (except red blood cells-RBC)
Where is the primary site of synthesis of Prostacyclins (PGI2)?

Vascular endothelium
What are the actions of Thromboxanes? (TxA2)?
- Vasoconstriction
- Promotes platelet aggregation
- Balances action of Prostacylins
What are the actions of Leukotrienes?
- Vasoconstriction
- Bronchoconstriction
- Increased vascular permeability
- Increased PMN (Polymorhphonuclear Neutrophils) chemotaxis

Author

anasolhowell

107325

Card Set

Mechanisms Eicosanoids

Description

Mechanisms Eiconsanoids

Updated

2011-10-08T22:00:06Z

Show Answers