-
What might be the first presenting sign of a defect in primary hemostasis?
- Defect in BV's or PLT
- Petechia/Ecchymoses
- (Thrombocytopenia or Thrombocytopathy)
-
What might be the first presenting sign of a defect in secondary hemostasis?
- Meleana (dark, tarry feces)
- Haematemesis (Bloody vomit)
- Hematuria
- Epitaxis Hemoptysis
- 1+ Hemotoma in tissues, cavities, joints
-
Collagen ->
- Tissue Activating Factor
- VW Factor
-
What tests analyze Intrinsic & Common Pathways?
- Acitvated Partial Thromboplastin Time (aPTT)
- Partial Thromboplastin Time (PTT)
- Activated Clotting (ACT) (DEC SENS)
-
What tests analyze Extrinsic & Common Pathways?
One Stage Prothombin Time (OSPT)
-
What tests analyze Platelet/Vascular Problems?
- PLT count
- BMBT
- Clot Retraction Time
-
What test is indicative of excess FDPs?
Clot Lysis
-
What test most accurately tests Intrinsic & Commmon Pathways?
APTT
-
What test is used to SCREEN for Intrinsic/Common Deficiencies?
ACT
-
Thrombocytopathy =>
- Increased Bleeding time
- Increased Clot Refraction Time
- Increased Clot Lysis
- Cytology
-
What is indicative of PLT regeneration?
++ MPV
-
What can lead to Decreased Fibrinogen
- Liver Dz
- Disfibrinogenemia
- ++FDPs
- Heparin Toxicosis
-
How are FBP's formed?
- 1. Plasminogen =>Plasmin
- 2. --> fibrin => FDPs
-
Which test is dependent on prothombin and its converstion to thrombin?
OSPT
-
Which 2 tests are performed together?
-
WVD, Warfarin toxicosis & Severe Liver Failure would => Increased...
-
Hemophilia, Heparin Toxicosis & Angiostrongylosis would => Increased...
-
Which test uses several Cap. Tubes?
- Coag Time
- (Dog/cat/pig=5-10m, bov=5-15m, Equ=20-30m)
-
Which test uses Siliceous Earth
Activated Coag Time
-
Which Test analyzes clotting time of citrated plasma Ca & +Thromboplastin
OSPT
-
What test measures the size of serum that forms around blood clot after 1 hour?
CRT (Clot Retraction Time)
-
What is a crude test for PLT function?
Clot Retraction Time (CRT)
-
What conditions => thrombocytopenias due to destruction?
- Chemicals
- Immune (destruction in BM)
- Neoplasia (MPD, LPD, Myelopthesis)
- Drugs (Phenylbut, cyclophosphomide & Estrogen)
- Cyclic Dyshemopoiesis
- Infections (erlichia, FeLV)
-
What conditions => thrombocytopenias?
Impaired Function
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