What are some contraindications that would make taking the antimycobacterial drug isoniazid (INH) risky for the patient?
History of allergy to isoniazid
History of liver damage from isoniazid
Severe liver damage from any cause
What are some contraindications that would make taking the monobactam drug aztreonam (Azactam) risky for the patient?
Viral infection
Lactation
What are some contraindications that would make taking the fluoroquinolone drug ciprofloxacin (Cipro) risky for the patient?
Allergy to any fluoroquinolone
Tendon pain
What are some contraindications that would make taking the antiparasitic drug chloroquine (Aralen) risky for the patient?
Allergy to drugs related to chloroquine
History of visual changes caused by drugs related to chloroquine
Porphyria
What are some contraindications that would make taking the macrolide drug erythromycin (E-Mycin) risky for the patient?
Allergy to erythromycin or other macrolide antibiotic
History of prolonged QT on ECG
What are some contraindications that would make taking the azole drug ketoconazole (Nizoral) risky for the patient?
Allergy to ketoconazole
Meningitis caused by fungi
Onychomycosis (fungal infection of the nails)
Ocular fungal infections
What are some contraindications that would make taking the antiparasitic drug metronidazole (Flagyl) risky for the patient?
Active CNS diseases
Severe blood disorders
What are some contraindications that would make taking the carbapenem drug imipenem (Primaxin) risky for the patient?
Allergy to carbapenems
Allergy to penicillin
What is a contraindication that would make taking the antiviral drug acyclovir (Zovirax) risky for the patient?
Allergy to acyclovir or valacyclovir
What are some contraindications that would make taking the cephalosporin drug cephalexin (Keflex) risky for the patient?
Allergy to cephalosporin antibiotics
Viral infections
What are some contraindications that would make taking the penicillin drugs amoxicillin (Amoxil) and amoxicillin and clavulanic acid (Augmentin) risky for the patient?
Allergy to penicillins
Infectious mononucleosis
Severe liver disease (amoxicillin and clavulanic acid)
What are some contraindications that would make taking the polyene antibiotic drug amphotericin B (Fungizone) risky for the patient?
Allergy to amphotericin
Lactation
What are some contraindications that would make taking the antimycobacterial drug rifampin (Rifadin) risky for the patient?
Allergy to rifampin
Obstructive gall bladder disease
Current meningococcal disease
What are some contraindications that would make taking the sulfonamide drug trimethoprim and sulfamethoxazole (Bactrim, Septra) risky for the patient?
Pregnant and near term, or nursing
Allergy to sulfonamides, trimethoprim, cyclo-oxygenase-2 inhibitors (celecoxib [Celebrex])
Megaloblastic anemia caused by folic acid deficiency
Infant younger than 2 months
Pharyngitis caused by group A beta-hemolytic streptococci
Hyperkalemia
Severely impaired urine creatinine clearance
What are some contraindications that would make taking the antibacterial drug tetracycline (Sumycin) risky for the patient?
Pregnancy (category D)
Child younger than 8
Allergy to tetracycline
Exposure to ultraviolet light
Serious renal or liver failure
What are some contraindications that would make taking the urinary tract antiseptic nitrofurantoin (Macrodantin) risky for the patient?
Allergy to nitrofurantoin
Impaired kidney function (with low urine creatinine clearance levels)
History of jaundice caused by gall bladder disease
Pregnant woman greater than 38 weeks of gestation
Labor or delivery, lactation
Infant younger than 1 month
What are some contraindications that would make taking the antibacterial drug vancomycin (Vancocin) risky for the patient?
Allergy to vancomycin
Allergy to corn products
What are some contraindications that would make taking the aminoglycoside drug Gentamicin (Garamycin) risky for the patient?