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why can aspirin be given in kids
reyes syndrome
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what population is aspirin contraindicated in
pts taking blood thinners
-
what are the labs to be considered in pts taking aspirin
- PT because it may increase clotting time
- my affect cholesterol potassium decreasing serum level
- T3
- T4
- cause abnormal liver function tests
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patient teaching on antiturberculosis drugs
that therapy could last between 6-24 months, but are unlikely to transmit infection after being antiboitics for 2-3 weeks, b12 may be needed supplemented, effects of meds to report are N/V, diarrhea, epigastric pain , anaphylaxis, neuropathy, optic neuritis, hepatotoxicity, blood dyscrasias
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Signs and symptoms of fluid overload
- increased blood pressure
- abnormal breath sounds (crackles)
- SOB
- electrolyte imbalance
- jugular vein distension
- weight gain
-
signs and symptoms of dehydration
- decreased blood pressure
- concentrated urine
- poor skin turgor
- flushed dry skin
- dry membranes in mouth
- tachycardia
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fyi if patient is allergic to penicillin they may also have an allergy to cephalosporins
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side effects of penicillins
- rash
- puritus
- diarrhea
- nausea
- fever
- anaphylaxis
- nephrotoxicity
- circulatory collapse
- cardiac arrest
- angioedema
-
cephalosporins (ceph)
same as penicllin and fatugue, oral vaginal cadidiasis, pseudomembranous colitis, nephrotoxicity, anaphylaxis
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what antibiotic if mixed with alcohol gives the disulfiram - antabuse like reaction
- cephalosporins
- the reaction includes severe vomiting, weakness, blurred vision, hypotension
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tetracyclines side effects
- N/V
- abd cramping
- gas
- diarrhea
- phototoxicity
- dizziness
- stinging
- anaphylaxis
- secondary infection
- heapttoxicity
- exfoliative dermatitis
-
what is the important population contraindicated in use of tetracyclines
- do not give to children and prego women because of discolaration of teeth
- do not take within 2-3 hours of antacids
- do not take with milk, iron supplements, magnesium cantainin laxatives or antacids
- drugs to lower lipid levels will reduce the levels of antibiotics
-
Macrolides (mycin) Erythromycin side effects
- same as other antibiotics
- along with ototoxicity
- hepatotoxicity
- suprerinfection
-
in patient teaching what is an important point on macrolides aka erythromycin
- do not take with fruit juice
- report pale stool
- dark urine
- jaundice
- itching
- rash hives
- difficulty swallowing
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what are some medications that will affect macrolides-erthromycin
- anesthetics
- anti convulsant drugs may cause toxic effects
- if on warfarin there may be a decrease in metabolism and excretion
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aminoglycosides (micin, mycin) side effects
gentamicin
- tinnitus
- anaphylaxis
- nephrotoxicity
- irreversible ototoxicity
- superinfections
- pts. with myasthenia gravis and parkinsons my have greather muscle weakness due to neuromuscular blockade
- vertigo
-
fluorroquinolones (floxin in 2nd gen)
ciprofloxan
- the same as the others
- restlessness
- corneal irritation in eye drops
- tendon rupture (kids)
- superainfections
- photosensitive
- pseudomembranous colitis
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whar are some important alerts concerning fluoroquinolones (cipro) concerning other meds
- antacids and ferrous sulfate - take at least 2 hours before these drugs
- may increase warfarin and theophylline
- report inflammation
- tendon pain
- dizziness
- restlessness
- stomach distress
- diarrhea fast heart rate
- confusion
- psychosis
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sulfonamides (sulf) common UTI med
trimethoprime and sulfethoxazole
bactrum, septra
side effects
- crystalluria
- steven johnson syndrome
- blood dyscrasia
- hepatic necrosis
-
pt teaching- sulfonamides (bactrum)
- intake of 3000 ml to avoid crystalluria
- hypersenitivity with diuretics (acetazolamides and tiazides)
- photosensitive
- report cramping
- hematuria fever
- if have megaloblastic anemis take trimethoprime (bactrim, septra)
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important things before antibiotic administration
- hard on liver and kidneys
- C/S
- eat foods with live cultures to help with flora
- take as directed, finish
- CBC
- WBC
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Colchicine
use
SE
- for gout and gouty arthritis
- SE- n/v, diarrhea, gi upset, bone marrow depression , kidney toxic, thrombocytopnia and agranuloctosis, leukopenia, aplastic anemiz
- take on empty stomach, monitor CBC
- report chane in urine output
- weakness
- pain
- diarrhea
- coombs test for hemolytic anemia
- swelling
- Increase fluids to 3-4 liters per day
- avoid alcohol
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H1 receptor antagonist
benadryl-1st gen
allegra-2nd gen
side effects
- urinary retention
- hyppotension
- extrapyramidal excitation
- agranulocytosis
- resp depression
- thick secretions
- dry mouth
- headache
- dizziness
- paradoxal excitement
- sedation
- hypersensitivity
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in giving H1 and H2 receptor antagonist what conditions may this med be contraindicated in
benedryl, allergra like drugs
- narrow angle glaucoma
- elderly (LOC)
- BPH
-
flonase, intranasal glucocorticoid
what would you monitor for & pt teaching
- cushings
- use decongestant before glucocorticoid
- may take 2-4 weeks for max effect
- use humidifier avoid swallowing when taking med
- clear nose before spray
- normal SE
- nasal irritaion
- burning
- sneezing
- dryness
- hypercorticism (if large amount swallowed
-
nasal decongestants Afrin
side effects
pt teaching
- nasal irritation
- burning
- sneezing
- headache
- severe vasoconstricion
- difficulty urination
- rebound congestion use 3-5 days only
- palpitations
- chest pain
- dizziness
- dry mouth
- confusion
- numbness
- tingling of face or limbs
- nosebleeds restlessness
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who should avoid nasal decongestants
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Pancreatic enzymes
prototype
administration
pt teaching
- pancrelipase
- cotazym
- pancrease
- give 1-2 hours before meals or with
- monitor for hypercapnia
- antacids will decrease effect of med
- do not give in pts allergic to pork
- contrindicated in pts with pancreatitis
- monitor liver labs
- avoid trigger foods
- observe stool
- lo fat
- small frequent meals
- positioning may help with pain
-
antiemetics reglan
side effects
administration
pt teaching
- side effects
- dry eyes, agranulocytosis, dry mouth , constipation, extrapyramidal excitation, drowsiness, photositive
- neuroleptic malignant syndrome
- administration/pt teaching
- reglan can be used to accerlate gastric emptying, or as and antiemetic, change positions slowly due to hypotension and dizziness
- report vomiting with or without blood if with a severe headache
-
diuretics
loops
lasix
side effects
administration
pt teaching
- lasix SE hypokalemia, ototoxicity, electrolye imbalances, tinnitus, nausea, diarrhea, dizziness, fatigue, blood dyscrasias, dehydration, circulatory collapse.
- pt teaching I & O
- BUN
- creatinine
- electrolytes (potassium)
- uric acid levels
- breath sounds
- hold med if BP is low, in dehydration and hypokalemia
-
pt teaching in lasix
- take in the morn when you will be near a BR
- expect to pee alot
- know S/S to watch for- weakness, cramps, changes in pulse rate
-
thiazide and thiazide like diuretics
chlorothiazide (diuril)
SE
Pt teaching
- same as loops + coma
- teaching same as loops
-
potassium sparing
spironactone
aldactone
SE
Admin
pt teaching
- minor hyperkalemia, headache, agranulocytosis
- blood dyscrasias
- dehydration
- hyponatremia
- dysrhythmias
- gynecomastia
- pt teaching
- like loops with these drugs do not give potassium supplements, somtimes combined with other diuretics to conserve potassium
-
vasopressin
use
s/s
overdose
- used for diabetes insipidus
- s/s headache, drowsiness, restlessness, confusion, coma. these can be avoided if pt reduces fluid intake
- overdose- excessive fluid retention, water intoxication
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