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What does zoonotic mean?
transferrable from animals to humans
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Name the three zoonotic atypical bacteria?
- C. psittaci
- F. tularensis
- C. burnetti
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Largest mode of transportation for zoonotic bacteria?
inhalation
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What is Psittacosis?
Sever infection w/ C. psittaci
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Signs and symptoms of Psittacosis?
- high fever
- hepatosplenomegaly
- jaundice
- dissemination & chronic inflammation
- cyanosis & anoxia
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What test is definitive of C. psittaci?
MIF
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DOC for C. psittaci?
Doxycycline (like other chalmydial infections)
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What is Tularemia?
disease of F. tularensis
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Signs and symptoms of Tularemia (rabbit fever)?
- necrotizing granulomas
- lobar pneumonia
- Bronchopneumonia
- bronchitis
- tracheitis
- bacteremia
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Where in the body does F. tularensis replicate?
endosomes
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What should be the titer and common test for F. tularensis?
- Titer >160
- test: DFA (fluorescence)
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DOc for F. turalensis
Streptomycin
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T/F the live attenuated vaccine will not prevent Tularemia?
T
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What are the two forms of C. burnetii?
- SCV (small cell variant): infectious, Category B
- LCV (large cell variant):
obligate intracellular, live in phagolysosome
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Most common disease caused by C. burnetii?
Q-fever
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Acute Q-fever signs and symptoms?
- high fever
- horrible HAs
- granulomas
- possible hepatitis
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chronic Q-fever signs and symptoms?
- more than 6 months
- Subacute endocarditis on artificial or damaged valve
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Common serological test for C. burnetii?
- IFA
- Acute: IgM to phase I & II ags, IgG to phase II ags
- Chronic: increased IgG/IgA to phase I ags, decline to Phase II ags
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DOC for C. burnetii
Doxycycline
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