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kepling
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Two pigments produed by P. aeuruginosa?
- Pyocyanin - blue
- Pyoverdin - green
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Acute, subacute, chronic of otitis media or sinusitis
- OM: acute & chronic
- Sinusitis: acute, subacute & chronic
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order of precendence for the three bacteria of OM & Sinusitis
- S. pneumoniae
- H. influenza
- M. catarrhalis
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for OM and Sinusitis, what is S. pneumoniae sensitive to?
Optochin
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DOC for OM?
- Amoxicillin
- ** tubes if chronic
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What is the fancy appearance of C. diptheria? Why?
Chinese letters w/ mtachromatic granules
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What is the phage-encoded exotoxin of C. diptheria?
Diptheria toxin: must be encoded into the phase to be effective
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What type of toxin is diptheria and how does it work?
- type: A-B exotoxin
- function: bind EF-2 to hault protein synthesis
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What 2 things does respiratory diptheria form in the pharynx?
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What occurs in the body if the diptheria exotoxin is not taken care of?
Systemic toxicity (myocarditis & demyelination)
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fucntion of blood agar in C. diptheria?
rule out hemolytic strept
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Function of Loeffler's medium in C. diptheria?
shows colonies
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Function of cysteine-tellurite agar in C. diptheria?
black colonies
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What test is performed to test for C. diptheria?
Elek test
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What neuralizes diptheria toxin?
diptheria antitoxin
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DOC for C. diptheria?
penicillin or erythromycin
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T/F there is a vaccine for diptheria?
T
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how do virulence factors P69 & FHA mediate their adhesion?
RGD sequences to bind to integrins
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What is the systemic toxicity of B. pertussis?
lymphocytic leukocytosis by inhibiting extravasation of lymphocytes (by pertussis toxin)
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T/F worldwide epidemics can still occur w/ whooping cough
T, every 2-5 yrs
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DOC for B. pertussis
Macrolides (erythro, azithro, clarithromycin)
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Name the to immunizations against B. pertussis?
- DTap (series)
- Tdap (booster)
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