Micro T2,L 23,24,25 Viral respiratory tract infections.txt

  1. What are the the three types of orthomyxovirus and which is most potent?
    • A,B,C
    • A is worse!!!
  2. Exampel of orthomyxovirus that causes influenza??
  3. Why is Type A orthomyxovirus (influenza) so dangerous?
    It can easily and frequenlty change genome
  4. What are the two methods utilized by Type A influenza to change genome?
    • antigenic drift: pt mutations of H or N proteins = vaccinations
    • antigenic shift: complete genome recombination of H & N proteins = pandemic
  5. What is the incubation period and persistent period of influenza
    • Incubation: 1-2 days
    • Persistence: 1 wk
  6. When is the flu dangerous?
    After it has left and another fever comes on. That is a sign of another infection.
  7. What bacteria take advantage of the immunocompromised state of a person w/ influenza?
    • S. pneumoniae
    • S. aureus
    • H. influenza type B (HiB)
  8. What two complications arise as a result of Influenza?
    • Reyes syndrome
    • Guillain-Barre syndrome
  9. What is Reyes syndrome? What age affected? Cause?
    • edematous encephalitis
    • Fatty alteration of liver
    • Age: 6 mo. -15 yr
    • cause: Influenza A/B
  10. What is the effect of Aspirin combined with chicken pox?
    Reyes syndrome
  11. What is Guillain-Barre syndrome?
    de-myelination of peripheral nerves
  12. T/f Influenza is a nosocomial infection?
  13. Function of Amantadine & Rimantadine?
    • Antibiotic treatment for Influenza Type A
    • - M2 protein inhibitor
    • - Stops uncoating/penetration
  14. Function of Zanamivir & Oseltamivir?
    • Influenza A & B ab
    • block neuraminidase
    • prevent sialic acid cleavage
  15. How long does a doctor have to administer a drug against influenza?
    48 hours
  16. What are the three components of an influenza vaccine?
    two A's and one B
  17. Three forms of influenza vaccine?
    • 1) Whole
    • 2) Split
    • 3) surface antigen
  18. T/F FluMist (live attenuated) should not be given to immunocompromised or old people?
  19. What year saw the highest death rate in young adults due to the flu?
Card Set
Micro T2,L 23,24,25 Viral respiratory tract infections.txt
Micro T2,L 23,24,25 Viral respiratory tract infections