Prodrugs

Heroin
- Prodrug for morphine
- Has acetyl groups instead of alcohols
- Crosses BBB more readily, then hydrolyzed into morphine
Nabumetone

Prodrug designed to reduce toxicity
Chloramphenicol

Prodrug designed to be more water soluble
Bambuterol
- Prodrug for Terbutaline
- Terbutaline experiences high first-pass metabolism
- Prodrug administration results in prolonged plasma concentrations of the drug

Author

jaguavai

106184

Card Set

Prodrugs

Description

Prodrugs from Pharm 410

Updated

2011-10-04T01:19:24Z