Anti-Microbials

• B-lactam
• inhibit bacterial cell wall

• B-lactam
• inhibit bacterial cell wall

• B-lactam
• inhibit bacterial cell wall

• NON-B-lactam
• inhibit bacterial cell wall

• Non-B-lactam
• inhibit bacterial cell wall

Cell lysis via formation of membrane pores

Inhibitor of protein synthesis via inhibiting microbial ribosomes

A: Inhibitor of protein synthesis via inhibiting initiation step by binding to the 30S ribosomal subunit, blocking the amino-acyl-tRNA. Blocks elongation too

U: G- bacteria by entering the periplasmic space and then pumped into cytoplasm. G+ by using energy

Minocycline & doscycycline pass directly through the lipid bilayer of both host and bacterial membranes

Bacteriostatic

Inhibitor of protein synthesis via inhibiting microbial ribosomes

Inhibitor of protein synthesis via inhibiting microbial ribosomes

Inhibitor of protein synthesis via inhibiting microbial ribosomes

Inhibitor of protein synthesis via inhibiting microbial ribosomes

Inhibitor of protein synthesis via inhibiting microbial ribosomes

Inhibitor of RNA synthesis for mycobacteria

Inhibit topoisomerases

Inhibit folic acid synthesis

Inhibit folic acid synthesis