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what are the 4 types of tissues?
Epithelial, connective, muscle, and nerve
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What are the 3 primary germs tissues developed from?
endoderm, mesoderm, and ectoderm
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mesoderm
forms connective tissues and muscles
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ectoderm
develops nervous tissue
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endoderm, mesoderm, and ectoderm
all make up epithelial tissues
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Tight juctions
are found where a leakproof seal is needed b/t cells (stomach and bladder)
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Adherens junctions
a dense layer of proteins "plaque" adhesion belt that keeps tissues from separation as they stretch and contract (when food moves through the intestines
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Desmosomes
as a "spot welds" hooks into the cytoplasm ( helps hold 2 cells together). Common among the epidermis and among cardiac muscle cells in the heart
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Hemidesmosomes
are hlf-welds that join cells to the basement membrane
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Gap Junctions
allows cells to communicate rapicly w/ one another. Are pores that allow small substances like ions to pass b/t cells (if cell gets sick/die it seals like a hatch to prevent damage to other cells)
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Epithelial tissues
- -lines every body surface, all body cavities, the external and internal lining of many organs
- -Protection, secretion, absorbtion
- -no blood vessels and has alot of nerves
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Simple Squamous Epithelium
a single layer of flat cells. In the air sacs of lungs, the lining of blood vessels & heart, and is epithelial membranes
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Simple Cuboidal Epithelium
a single layer of cube shaped cells. Lining tubules of the kidneys and glands
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Simple Columnar Epithelium
a single layer of column like cells, common in the diegestive tract. (w/ goblet cells-cilia, microilli, mucous)
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Goblet cells
are simple columnar cells that have the ability to secrete muscous( cilia-fallopin tubes and lungs, microvilli-like sponges absorbs in digestive system, & mucous-slightly sticky fluid)
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Pseudostratified Columnar Epithelium
appears to have layers but doesnt, all cells are attached to the basement membrane in a single layer
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Stratified Squamous Epithelium
apical (free) surface squamous(flat) cells. SKIN
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Stratified Cuboidal Epithelium
apicla surface: 2 or more layers of cube-shaped cells ( in sweat glands/ducts and part of the males uretha)
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Transitional Epithelium
cells change shape depending on the state of stretch in the tissue (ex. bladder-in full bladder cells are flattened)
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Pseudostratified ciliated columnar
characteristic of the upper respiratory tract
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What are the 2 types of Glands?
Endocrine & Exocrine
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Endocrine Gland
secrete contents directly into blood, act on the entire body. Hormones (ex. thyroid and adrenal glands)
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Exodrine Glands
secrete contents into a duct, act in a certain location (ex. sweat gland)
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What are the different types of exocrine glands?
- Serous glands- produce and secrete sweat, milk, tears, digestive juices
- Mucous glands- produce and secrete mucin which forms mucus with water
- Mixed glands-salivary glands contain serous and mucous cells and produce a mixture of the two types
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What are the functional glands?
Merocrine, holocrine, and apocrine
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Merocrine secretions
the gland package secretions in secretory vesicles and releases it product by exocytosis. No part of the gland is lost or damaged. (Salivary gland)
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Apocrine secretions (combo of merocrine and holocrine)
pack secritory vessicles in apicla region, the ends buds off leaving a milky ordorless fluid. (ex. mammary gland, )
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Holocrine secretions
produced by rupture of the plasma membrane releasing the entire cellular contents and killing the cell(ex. sebaceous gland)
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Connective tissue
- is usually highly vascular and supplied w/many nerves.
- tendons have little blood and cartilage has no blood but are both C.T.
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3 major components of C.T.
Protein fibers and ground substance and sparse cells-surroundedby an lot of extracellular matrix
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Fibroblasts
the most common C.T., they secrete protein fibers (collagen, elastin, and reticular fibers)
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Other common C.T. cells
- Macrophages-immune cells
- Adipocytes-store triglycerides
- chondrocytes-make the various cartilaginous c.t.
- Ostcocytes-make bone
- Medlanocytes-pegment cells
- mast cells- secrete histamine/stimulate inflation
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C.T. 3 Protein common fibers
- collagen fibers-most commonstrong,strecth-resistant(bone, tendons, ligaments)
- elastin fibers- rubber-like flexible protein(found in skin, blood vessel walls and lungs)
- reticular fibers-form interwoven framwork(found around fat cells, nerve fibers, and smooth/skeletal muscle cells)
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ground substance
supports and binds cells together, provides a medium for the exchange of materials, stores water, and actively influences cell functions
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Embryonic connective tissue
- Mesenchyme-form into any tissue type stem cell
- Mucous-umbilical cord
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Mature Connective tissue
Loose, Dense, Cartilage, Bone, & Fluid
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Loose connective tissue
- areolar c.t.-fills spaces b/t organs and under skin (around blood ves., nerves, body organs
- adipose c.t.- deep to the skin & around organs & joints (fat cells)
- reticular c.t.- reticular fibers & cells (found in liver, spleen, lymph nodes)
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Dense connective tissue
- dense irregular-strength collagen fibers and a few fibroblasts ( found in the dermis of skin, and membrane capsules around organs)
- dense regular-parallel bundles of collagen fibers (forms tendons, most ligaments)
- elastic-branching elastic fibers and fibroblasts (found in lungs, trachea, & bronchial tubes)
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Cartilage connective tissue
- Hyaline cartilage-most abundant, provides a smooth surface for joint movement (ends of long bones,parts of ribs, nose, etc)
- Fibro cartilage-thick bundles of collagen fibers, strong & tough (in b/t vertebral of spine supports huge loads up and down the long axis of the body)
- Elastic cartilage-less collagen more elastic fibers allows flexibility (make up malleabel part of external ear)
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Bone connective tiusse
minreal reserve, protects organs, aids in movement (support the system and body)
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Fluid connective tissue
- Blood-has many cells
- Lymphs-
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Muscular tissue
makes up large % of body's weight, create motion, maintain posture, move substances by peristaltic contractions, and generate heat through thermogenesis
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3 types of muscular tissue
- skeletal-in the skeleton, movement heat posture, striated multinucleated fibers parallel, voluntary
- cardiac- heart, pump blood continuousl, striated one central nucleus, involuntary
- visceral (smooth muscle)- G.I tract,blood vessels, eye, uterus.Peristal, blood pressure, pupil size,erects hairs.No striations one central nucleus involuntary
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nervous tissue
- consist of nerve cells(neurons) and neuroglial cells.
- central nervous system-brain and spinal cord
- peripheral nervous system-peripheral nerves
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Neurons
- Functional unit, conducts impulses from one cell to another.
- most neurons have cell body, axon, dendrites, and axon terminals
- Gather info at dendrites and process it in he cell body-->transmit info down their axon to the axon terminals
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Multipolar neurons
have serveral dendrites and only one axon located throughout the brain and spinal cord.Majority of neurons in the human body are multipolar
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Bipolar neurons
have one main dendrite and one axon. Used to convey special senses:sight, smell, heraring and balance. (in retina of the eye and inner ear, and olfactory)
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Unipolar Neurons
contain one process which extends from the body and divides into a central branch that functions as an axon and as a dendritic root. Employed for sensory neurons that convey touch.
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Neuroglia
support cells of the nervous system. Aid in conducting impulses
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Integument (skin)
- Cutaneous membrane-epidermis, dermis, hypodermis
- accerssory structures- hair, nails, exocrine glands
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Functions of the Integument
- Protection-filters UV light, prevents loss of body fluids, inhibits invasion of bacteria
- Thermal regulation-sweat glands/loss of water,alt, urea
- Lipid storage-fats
- Vitamin D synthesis-
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Main layers of skin
- Epidermis-has keratinized, stratified squamous epithelium. Thick vs thin skin
- Dermis- papillary layer (areolar c.t), reticular layer (dense irreg. c.t)
- Hypodermis/Sub Q- loose c.t (adipose and areolar) connect underlying muscle and bone to dermis contains large blood vessels
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Stratum basale (deepest layer)
- stem cells onthe basement membrane (mitotic)
- continual cell division w/ daughter cells pushed to the next layer
- contains melanocytes-melanin synthesis and storage
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Statum spinosum
- 5-6 layers of cells w/ spiny cytoplasmic extensions (keratinocytes)
- some cell division does occur in layer
- contain langerhans cells:macrophages for innume response
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Stratum granulosum
- 2-5 cell layers that produce keratin and keratohyalin
- keratohyalin limits dehydration, cross links keratin fibers
- organelles of celss start to disintegrate; apoptosis
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Stratum Lucidum
- only in thick skin (palmar/plantar)
- glassy layer of flat cells packed w/ keratin
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Stratum Corneum (superficial layer)
- varying number of individual cell layers
- tightly packed dead, keratinized cells (squames)
- continuously shed-constantly replaced
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Skin color is derived from 3 pigments
- Carotene-least common; orange-yellow pigment from diet
- Hemoglobin-pigment of blood;varies w/ oxygen, color tinges epidermis for dermis
- Melanin- primary determinant of variability in skin color, produced by melanocytes in stratum basale
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Apocrine sweat gland (skin)
- found in axilla, anal, groin regions, & around nipples
- secrete a sticky, cloudy & odorous secretion onto hair follicles
- secretion provides nutrient source for bacteria
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Merocrine/Eccrine sweat gland
- widely scattered over body surface
- secrete water, electrolytes, and metabolites onto the surface
- evaporation cools skin and body
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Sebaceous sweat gland
- produce sebum into hair follicle to lubricate hair and skin
- most active late in fetal development and puberty
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Ceruminous gland
- located in external ear
- secretes cerumen (ear wax)
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Dermis
- Papillary layer-more pronounced on palms and soles to form surface ridges on epidermis; contain cappillary beds and nerve endings
- Reticular layer-deepest layer of dense irregular c.t; bundles of collagen fibers extend through reticular layer & hypodermis;elastin in layer affected by UV, age, hormones
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Errector pili muscles
casues the hair to stand up known as googe bumps
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Nails
- composed of heavily conrnified cells that develop from specialized stratum corneum called nail matrix
- protect distal phalanges from damage/distortion during manipullation activity
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Hair
extends across entire body except palmar/plantar surfaces, lips, and genitalia
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Hair Follicle
- Root- part of the hair set in the follicle
- Papilla-small projection at bulb; provides blood suppy
- Shaft- keratin in 3 layers: Medulla(inner)-soft keratin, Cortex-hard keratin, Cuticle(outer)-scales of keratin
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