Parisitology - Leishmaniasis

Leishmania vector

Sandflies
Cutaneous Leishmaniasis - How do you get it?
- Bite of infected sandfly
- Contact infection possible
Cutaneous Leishmaniasis - Presentation?
- Small red itchy papule - grows to ulcer
- Usually heal spontaneously
- Lymphadenopathy
Cutaneous Leishmaniasis - Diagnosis?
- Microscopic ID by aspiration of fluid under ulcer bed
- Montenegro skin test
Cutaneous Leishmaniasis - Pathogenesis?

Parasites proliferate as amastigotes in macrophages and endothelium
Cutaneous Leishmaniasis - Treatment

Sodium stibogluconate (Pentostam)
Mucocutaneous Leishmaniasis - Where?

S. America
Mucocutaneous Leishmaniasis - Presentation?
- Ulcers on oral or nasal mucosa
- Cutaneous lesions, but more frequent and large
- Nasal septum destroyed (all soft parts of nose and mouth at risk)
- Death from secondary infection
Mucocutaneous Leishmaniasis - Treatment?

Sodium stibogluconate (Pentostam)
Visceral Leishmaniasis common name

Kala-azar
Visceral Leishmaniasis - Differences?

Protozoa attacks systemically
Visceral Leishmaniasis - Presentation?
- Hepatospenomegaly
- Anemia
- Progressive weight loss
- Ascites
Visceral Leishmaniasis - Treatment?
- Sodium stibogluconate (Pentostam)
- Amphotericin B
Leishmania culture

Author

zf2010

104053

Card Set

Parisitology - Leishmaniasis

Description

Leishmaniasis

Updated

2011-09-25T00:26:49Z

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