351 Psych Antipsychotic drugs

  1. What is Benztropine (Cogentin)?
    • -Anticholinegic, used to treat EPSE
    • -Most frequently prescribed.
    • -Do not give with TD
    • -Can be given Oral, IM or IV
  2. What is Biperiden (Akineton)?
    • -Anticholinergic drugs
    • -Used to treat EPSE
  3. What is Diphenhydramine (Benadryl)?
    • -Anticholinergic
    • -Used to treat EPSE
    • -Can cause some sedation
    • -Less potent than Benztropine (Cogentin)
  4. What is Trihexyphenidyl (Artane)?
    • -Anticholinergic
    • -Not available in parenteral form, use for acute dystonias is limited.
  5. What is chlorpromazine (Thorazine)?
    • -Traditional, low potency
    • -Results in more anticholinergic and antiadrenergic effects, and less EPSEs
  6. What is Thioridazine?
    • -Traditional, low potency
    • -Not prescribed as much, can cause death
    • -Has been therapeutic in behavioral problems.
    • -Upper limit of 800 mg/day because of pigmentary retinopathy (decreased visual acuity, impaired night vision, pigment deposits on the fundus.)
  7. What are the moderate potency traditional antipsychotics?
    • -Loxapine (Loxitane)
    • -Molindone (Moban)
    • -Perphenazine (Trilafon)
  8. What is Fluphenazine (Prolixin)?
    • -Traditional, high potency
    • -Long acting Fluphenazine decanoate (prolixin decanoate) injection can be given every 2-3 weeks
  9. What is Haloperidol (Haldol)?
    • -Traditional, high potency
    • -Cause more EPSE and fewer anticholinergic side effects.
    • -Used extensively in older adults and pediatric psychiatry.
    • -Threat of aggressive behavior, can be used in combination with Ativan.
    • -Haloperidol Decanoate, long acting form
  10. What is Chlorpromazine?
    • -First atypical antipsychotic
    • -Reduced or no risk for EPSE
  11. What is Clozapine (Clozaril)?
    • -Atypical, works on both positive and negative symptoms
    • -Causes agranulocytosis
    • -Excessive salivation
    • -Myocarditis
    • -less risk for EPSE
  12. What is Risperidone (risperdal)?
    • -Atypical antipsychotic
    • -Favorable profile for positive and negative symptoms
    • -Low side effects
    • -A long acting IM (Risperdal Const) available
  13. What is Olanzapine (Zyprexa)?
    • -Atypical, similar to Risperdal
    • -Causes weight gain, Metabolic syndrome
    • -IM and oral form
    • -approved to treat acute mania
  14. What is Quetiapine (Seroquel)
    • -Atypical
    • -Few anticholinergic effects
    • -Orthostatic hypotension
    • -Appears to improve serum prolactin levels and cognitive factors
    • -Produces a sedative effect
  15. What is Ziprasidone (geodon)?
    • -Atypical
    • -Causes few EPSEs, few anticholinergic side effects
    • -Less weight gain than other atypical
    • -Lengthens the OTc interval
    • -Absorption is increased when give with food
  16. What is Aripiprazole (Abilify)?
    • -Dopamine system stabilizer (DSS), third generation of antipsychotics
    • -Increases dopamine where needed and decreases dopamine where needed
  17. What is Asenapine (Saphris)?
    • -Latest atypical drug
    • -Sublingual tablet
    • -Approved for acute schizophrenia and bipolar disorder
    • -Low EPSEs, higher cases of akathisia.
Card Set
351 Psych Antipsychotic drugs
351 Psych Antipsychotic drugs