-
hormones that regulate blood cell number
cytokines
-
types of granulocytes
- neutrophils
- eosinophil
- basophils
-
-
granulocytes
- multilobed nucleus
- phagocytic
- specific granules- bind neutral, basic, acidic dye
- azurophilic- lysosome, dye purple
-
neutrophil
- polymorphonuclear
- neutral staining
- bacteria, fungus, cell debris
- 4-8 hrs in circulation
- 4-5 days in tissue
-
eosinophil
- stain red
- 1-3% total WBC
- allergic reaction- release enzymes detox agents
- parasitic- attach w/ surface markers release hydrolytic enzymes
-
basophil
- .3-.5%
- allergic & hypersensitivity reactions
- contain heparin & histamine
-
lymphocytes
- 30%
- B-humoral-mediated immunity
- T- differentiate in thymus; helper-activate immune system, cytotoxic-cell mediated immunity
- NKC- innate or natural immunity destroy foreign cells
-
monocyte
- 3-8%
- azurophilic
- histiocytes- connective tissue
- microglial cells- brain
- kupffer cells- liver
- tissue macrophage
- activate lymphocytes by presenting antigen to T
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