Histamines Antihistamines

H₁
- Smooth muscle of blood vessels, bronchi, intestines
- Endothelium
- CNS
H₂
- Stomach acid secretion
- Smooth muscle of some vessels
- Cardiac muscle
- Mast cells
- CNS
H₃

Autoreceptor on histamine releasing neurons
H₁ antagonists (1_st Generation)
- Diphenhydramine
- Promethazine
- Chlorpheniramine
- Pyrilamine
- Cyclizine
- Meclizine
- Cyproheptadine
H₁ antagonists (2_nd Generation)
- Fexofenadine
- Loratadine
- Desloratadine
- Cetirizine
Other antihistamine compounds
- Cromolyn sodium
- Stabilizes mast cells, preventing release of histamine
H₂ antagonists
- Cimetidine (inhibits p450)
- Ranitidine
- Famotidine
- Nizatidine

Author

skycloud

103839

Card Set

Histamines Antihistamines

Description

Histamine Actions and Antagonists

Updated

2011-09-23T17:00:01Z

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