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Antibacterial Agents

  1. Inhibition of cell-wall synthesis
    • Penicillin
    • Vancomycin
    • Cephalosporin
    • Imipenem/meropenem
    • Aztreonam
  2. Inhibition of bacterial protein synthesis
    • Aminoglycosides
    • Chloramphenicol
    • Macrolides
    • Tetracyclines
    • Streptogramins
    • Linezolid
  3. Inhibition of DNA replication or transcription
    • Fluorquinolones
    • Rifampin
  4. Inhibition of nucleic acid synthesis
    • Trimethoprim
    • Flucytosine
  5. Inhibition of folic acid synthesis
    • Sulfonamides
    • Trimethoprim
    • Pyrimethamine
  6. Disruption of cell membrane function
    • Azole
    • Polyene antifungals
  7. Penicillin
    • binds to PB protein
    • inhibits transpeptidase
  8. Aminoglycosides
    • Cause translational misreading
    • Gentamicin
    • Neomycin
    • Streptomycin
  9. Macrolides
    • Interfere with translational translocation
    • Azithromycin
    • Erythromycin
  10. Quinolones
    Bind topoisomerase
  11. Chloramphenicol
    Inhibits peptidyl transferase
  12. Tetracycline
    Blocks binding of amino-acyl tRNA
  13. Sulfonamindes
    Prevents production of dTMP
  14. Lincosamides
    • Interferes with translocation
    • Clindamycin
  15. Rifampin
    • Binds DNA dependent RNA polymerase
    • Prevents transcription
Author
skycloud
ID
103825
Card Set
Antibacterial Agents
Description
Antibacterial drugs and mechanisms of action
Updated

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