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Attachment to host cells
All gram + have it
Lipoteichoic acid
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Antiphagocytic polysaccharide
- Capsule
- Salmonella typhi, Neisseria meningitides, Klebsiella pneumoniae, Haemophilus influenzae, Strep pneumoniae, Cryptococcus neoformans, Pseudomonas aeruginosa
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Binds Fc of IgG
Inhibits phagocytosis
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-
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Antiphagocytic
Antigenic variation
Pili of Neisseria gonorrheae
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Hydrolysis of ground substance
- Hyaluronidase
- Group A strep
-
Hydrolysis of collagen
- Collagenase
- C. perfringens
- prevotella melaninogenica
-
Increases pH of micro-environment
Contributes to kidney stones
- Urease
- PUNCH
- Proteus, Ureaplasma, Nocardia, Cryptococcus, Helicobacter
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Destroys cell membranes
- Lecithinase (alpha toxin)
- Clostridium perfringens
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Detoxifies hydrogen peroxide
- Catalasea
- Staph, Pseudomonas, Aspergillus, Candida, Enterobacteria
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Destroys IgA
- IgA protease
- Promotes colonization of mucosal surface
- Neisseria, Haemophilus, Strep pneumo
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Detoxifies oxygen radicals
- Oxidase
- Involves cytochrome C
- Neisseria
- Most gram - except Enterobacteria
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Promotes fibrin clot
- Coagulase
- Staph aureus
- Yersinia pestis
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