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9/13 Protein Structure
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AA Linked by peptide bonds
Disulfide Bonds
Primary Structure of Proteins
Alpha Helix
Secondary Structure of Proteins contain what
Quaternary Structure
Hemoglobin is what type of protein?
Alpha Helix
Folded Protein
Teritary Structure
primary structure
The Amino Acid Sequence of a protein is referred to as its
DNA (Genes)
Each protein has a unique AA structure determined by what
determin MOA
determine 3D shape
Molecular Pathology --> Cancer
Why is it important to know the structure of proteins/amaino acid sequence of proteins?
Sickle Cell Anemia
Cancer
2 Examples of single AA substitutions
Always On
constitutively active AKA
Unregulated cell growth --> Cancer
if an enzyme is constitutively active what happens
Mutation of Glu6 to Val in hemoglobin
Which enzyme mutation cx Sickle Cell Anemia
Alpha Helixes
Beta Helixes
What are the 2 main secondary structures?
Coil and Turn
beta sheets and polypeptide segments without a distinctly folded arrangement are called
Author
Anonymous
ID
103624
Card Set
9/13 Protein Structure
Description
9/13 Protein Structure
Updated
2011-09-22T19:04:34Z
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