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Hypotonic
Water is pulled out of vessels and into cells
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Hypotonic IV fluids are used to _____
Prevent and treat cellular dehydration
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Hypotonic Solutions
- D5W, 0.45 NS, 0.225 NS
- Glucose solutions are hypertonic in the bag, but have a hypotonic effect on the cells due to rapid metabolization of dextrose
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Nursing Considerations of pt receiving hypotonic solutions
Frequent monitoring of VS, LOC, and cirulation to detect depletion of vascular volume and cerebral cellular edema
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Hypertonic
- Very Rare
- Cause water to be pulled from cells and into the vessels
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Hypertonic IV Solutions
- Saline solutions greater than 0.9%
- Dextrose solutions (10 or 50%) used on a limited basis to treat pt with hypoglycemia
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Hypertonic Solutions should be given to pt when _____
Serum Sodium is dangerously low (115 or less)
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Nursing Considerations of pt receiving hypertonic solutions
Monitor VS, neurological status, lung sounds, urine output, serum sodium levels to avoid hypernatremia and vasular volume overload
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Antidiuretic Hormone
Synthesized by the hypothalmus and secreted by the pituitary gland
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ADH release is triggered by:
- Drop in BP or blood volume ORRise in osmolality causing the kidneys to reabsorb more water
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ADH release is inhibited by:
- A rise in BP or blood volume ORA drop in blood osmolality
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Aldosterone
Adrenal gland hormone that conserves sodium in the body by causing the kidneys to retain sodium and extrete potassium in its place
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Aldosterone release is triggered by:
Drop in BP, blood volume, serum sodium, or a rise in serum potassium
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Aldosterone release causes the kidneys to ____
Reabsorb more sodium into the blood increasing serum sodium levels, and water follows sodium to raise vascular
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Aldosterone release is inhibited by:
Rise in BP, blood volume, or sodium or a drop in potassium level
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Glucocorticoids (Cortisol)
- Hormone produced and released by the adrenal gland when the body is stressed
- Promotes renal retention of sodium and water
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Atrial Natriuretic Peptide (ANP)
- Cardiac hormone found in the atria
- Lowers blood volume and BP
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ANP is released when ____
Atria are stretched by high blood volume or high BP
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Brain Natriuretic Peptide (BNP)
- Cardiac hormone found within ventricles
- Decreases blood volume and pressure
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BNP is released when ____
Blood volume and pressure withing the ventricles are increased
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Isotonic Fluid Loss
- Fluid and solute are lost in proportional amounts so osmolality remains normal and no osmotic force is created
- Can lead quickly to shock
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Causes of Isotonic Fluid Loss
- Hemmorrhage (hypovolemia)
- GI losses
- Wound drainage or wound suctioning
- Fever
- Burns (#1 problem)
- Diuretics
- Third space fluid shifts
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Treatment of Isotonic Fluid loss
- Isotonic Solutions
- Blood Products
- Colloid volume expanders
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Hypertonic Dehydration
- More water is lost than solute (primarily sodium)
- Serum osmolality is elevated, so fluid is pulled into vessels from cells causing cellular dehydration
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Causes of Hypertonic Dehydration
- Inadequate fluid intake
- Prolonged isotonic fluid losses when body is no longer able to compensate
- Prolonged watery diarrhea
- Diabetes Insipidus
- Increased solute intake
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Causes of Third Spacing
- Injury or inflammation
- Malnutrition
- Liver dysfuntion
- High vascular hydrostatic pressure as seen in heart failure
- Renal failure
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Assessment findings in pt with Fluid volume Defecit
- Thirst
- Urine output less than 30 cc/hour
- Concentrated, dark urine with high specific gravity
- Dry skin with decreased turgor and elasticity; dry mucous membranes
- Dry tongue with longitudinal furrows
- Decreased tearing and dry conjunctiva
- Sunken eyeballs
- Flat neck veins and poor peripheral vein filling
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Lab Findings of Fluid Volume Deficit
- Normal or high HCT
- High urine specific gravity
- Serum osmolality elevated >300
- Hypernatremia
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Therapeutic Management of Fluid volume deficit
- Oral fluid volume replacement
- Avoid drinks with high sugar and salt content (hypertonic)
- Avoid caffeine (mild diuretic)
- Administer isotonic fluids
- Administer blood transfusions for hemorrhage
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Evaluation of adequate Fluid Volume
- Urine output and concentration >30 cc/hr
- Stable heart rate and blood pressure lying and standing
- Skin and mucous membranes moist with normal turgor and elasticity
- Normal mental status and behavior
- HCT, BUN, Serum osmolality, serum electrolytes return WNL within 48-72 hours
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Lab values of Fluid Volume Excess
- Hematocrit and BUN decreased due to hemodilution
- Serum osmolality is low <275
- Serum sodium is low <125
- Chest x-ray may show plerual effusions
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