-
This endogenous (internally produced) opiod neurotransmitter peptide is responsible for runner's high, fever reduction, and orgasm.
Endorphin [Frontal lobe activation in Runner's High]
-
This lipid neurotransmitter is used to treat pain, anxiety, Parkinson's disease, and obesity. It can reduce eye pressure and increase appetite.
endocanabinoid
-
In these disorders of the basal ganglia, endocanabinoids can adjust to control imbalanced tremors
Huntington's & Parkinson's
-
This stimulant is the most commonly used drug in the world
caffeine [inconclusively addicting]
-
caffiene (an antagonist) works to inhibit this nucleoside, which is energy controling, anti-arousal, and plays a role in promoting sleep.
Adenosine [Adenosine levels increase with every hour of wakefulness]
-
This soluble gas is used in Viagra. It increases relaxation in muscles and increases bloodflow to counteract detumescence.
Nitric Oxide
-
Using a stereotaxic devise, creating a ________ current kills the tissues--- axons, soma, etc. - of everything that passes through the region.
(RF) Radio Frequency Lesion
-
In animal research, a _______ apparatus holds the animal's head, maintains proper orientation, etc. It is sometimes used in human neuorsurgery.
Stereotaxic
-
________ methods = brain stains
Histological
-
A _______ mouse or other animal has a targeted mutation.
"knockout"
-
______ magnetic stimulation can be used to create "temporary" lesions. Also may be useful in treating depression?
Transcranial (TMS)
-
A(n) ____ lesion stimulates neurons to death.
excitotoxic
-
A high resolution, very fast scanner that allows researchers to view the brain's regional metabolism.
fMRI (functional Magnetic Resonance Imaging)
-
Put your head in a donut shaped ring, an x-ray passes through your head, and other side has a detector that measures radioactivity that it detects.
CT Scan (Computerized Tomography Scan)
-
Using stereotaxic equipment, control animals usually receive ____________ lesions.
"sham"
-
Person receives a radioactive injection-- when the molecules decay they are detected by a computer.
PET Scan (Positron Emission Tomography Scan)
-
A(n) ________ microscope has extreme powers of magnification (think "ant face").
electron
-
Destroying (not removing) a brain portion to study its effects
experimental ablation
-
_______ is where macroelectrodes read neuron cluster voltages in the brain.
EEG (Electroencephalogram)
-
the inability of the brain to make sense of or make use of some part of otherwise normal visual stimulus.
visual agnosia (loss of knowledge)
-
the inability to recognize familiar objects or faces.
prosopagnosia (prosopon- face, agnosia- loss of knowledge)
-
Specialized neurons that receive information from the senses
sensory receptors
-
process where information from the senses is received and changed to appropriate neural impulses
transduction /transduced
-
What portion of the brain's cerebral cortex is involved in vision?
20% -- 1/5
-
this is picked up by the eye to allow for sight
electromagnetic radiation
-
this is measured in wavelength... from 400-700; or blue-red
visual spectrum
-
This part of the eye causes neurons to fire
retina
-
this connects the eye to the CNS
optic nerve
-
eye movement - cooperation of both eyes to focus on something
Vergence movement
-
eye movement- a jumping focus on several points such as reading
Saccodic movement
-
eye movement - moving to maintain an image of something, such as a runner
pursuit movement (moving things are seen better)
-
Rods percieve _______ in the perephial
(low) light
-
Cones perceive _______ in the fovea (center) of the eye (black/white)
color
-
when an eye perceives electromagnetic radiation and it is sent through the CNS/LGN to the visual cortex. This is an example of _______
transduction
-
Rods and cones are _______ receptors
Photo
-
A group of cells in the thalamus that is a relay medium between the retina and the visual cortex
Lateral Geniculate Nucleus (LGN)
-
Processing area for visual information: retina > thalamus (LGN) > ___________?
Primary visual cortex / V1 /Striate cortex
-
This is an inherited genetic trait with inability to distinguish certain colors
color blindness
-
the ganglion cells are responsible for this color distortion -___________
rebound effect
-
when neurons affect neighbor neurons (inhibit them)
Lateral inhibition
-
where different neurons respond to different spatial orientations (such as the abe lincoln pixel slides)
spatial filtering
-
this is involved in depth perception
Retinal disparity
-
Impaired color vision (can be hemisphere based) (sharpness & accuity not affected)
Cerebral achromatopsia
-
the loss of concept or knowledge
agnosia
-
prosopagnosia is a symptom of _______
visual agnosia
-
This is responsible for facial recognition (in the temporal cortex) Damage to this causes impaired facial recognition. MAY BE CONNECTED with prosopagnosia and autism!
Fusiform face area (FFA)
-
In Fusiform face area FFA studies, what face cues did the FFA respond to?
The real face, and an implied, blurred face. [also note greeble family learning study.]
-
where the occipital and temporal lobe meet, it is activated by human body forms and body movement.
Extrastriate body area (EBA)
-
In the occipital lobe/cortex, this activates when processing scenes and backgrounds
Parahippocampal place area (PPA)
-
term for "hearing"
audition
-
Loss of ability to perceive or produce music
Amusia (caused by damaged temporal cortex/gyrus)
-
musical voice / emotionality
prosody
-
Match the physical form (A) of soundwaves with the perceptual (B) form:
A: Complexity, Amplitude, Frequency ;
B: Pitch, Loudness, Timbre
- Complexity - Timbre
- Amplitude - Loudness
- Frequency - Pitch
-
a level of 110 of this measurement for more than one minute can cause hearing loss/damage
decibels
-
term for ringing ears
Tinnitus
-
This helps collect soundwaves for hearing:
The external ear (pinna)
-
vibrations per second is measured in this
Hertz
-
3 main stages of processing sound:
1. Sound transmits into the auditory canal,
2. sound hits the __________,
3. then moves to the _________ which processes sound (this is a pathway of transduction!)
- Ear drum (tympanic membrane);
- Cochlea
-
The shell shaped cochlea processes High/low? frequencies at the base, while it processes high/low? frequencies at the top
-
______ contains the recpetor cells for hearing
Basilar membrane
-
_______ bend to facilitate neuron firing
Hair cells
-
What is the cause of ringing ears?
damage to the hair cells
-
(probably important) Transduction pathway of hearing:
1: _________ (in the hindbrain)
2: ___________ _________ (midbrain)
3: ______ _______ ________ __ __ _______(forebrain)
4: __ _______ _______ (temporal cortex/forebrain)
- 1:Medula
- 2: inferior colliculus
- 3: medial geniculate nucleus of the Thalamus
- 4: A1 auditory cortex
-
In the basilar membrane,
high or low? frequency excites hair cells near the base, while high or low? excite hair cells near the top/apex
-
Cochlear implants are surgically placed in the ear to aid deaf people. This is relevant somehow to...
place coding
-
Are hair cells stimulated more by loud or soft sounds?
loud
-
localized perception of sound; sound hits one ear before it reaches the other
Binaral differences in sound
-
judgment of horizontal position of a sound, 0-340º
Azimuth
-
cortex of where judgment of sound direction takes place
in the dorsal auditory cortex
-
cortex where judgment of what a sound is takes place
in the ventral auditory cortex [responsible for amusia]
-
not able to recognize a sound
auditory agnosia
-
Sound is ...(? missing notes).. which hemisphere and lobe?
Left Hemisphere, temproal lobe
-
processing of this starts sub-cortically
music!
-
harmony (2 voices at the same time) is processed in the _____ cortex
Frontal
-
Beat is processed in the Left or Right? ________ cortex
Rhythmic patterns in the Left or Right? ________ cortex
- Right auditory
- Left auditory
- [temporal lobe]
-
professional muscians are said to have larger ________ (which first analyzes sound) than non-musical people!
Heschls' gyrus
-
How many people in the USA are hard of hearing?
4% are deaf and hearing impaired
-
The 3 types of deafness:
- Conduction
- Nerve/sensorineural
- Central
-
There is interference to the outer/ middle ear. the CNS is not damaged. this is ________ deafness
conduction
-
This deafness involves impaired cochlea, hair cells, etc. It is not repairable with a hearing aid
nerve/ sensorineural deafness
-
This deafness is caused by brain lesions
Central deafness
-
Hair cells regrow in mamals?
NO [also autotoxic drugs can cause deafness FYI]
-
A condition where a person can read, speak, etc. but cannot understand speech. May involve Wernicke's Area
word deafness
-
understand the differences in recognition vs. comprehension, such as hearing foreign language
O.K.
-
Inside the ear there are _________ sacs that help us establish balance and spatial orientation
vestibular
-
inside each ear there are 3 ___________ which help in aiding balance and adjusting for head movement.
semicircular canals
-
vestibular senses provide...
balance, orientation, eye and head adjusting and syncronizing, etc.
-
the __________ nerve connects and recieves positional information
vestibular nerve [ located in hind and midbrain]
-
Things that can happen when the vestibular system is damaged:
blurring, dizziness, nausea, fatigue, losing balance [such as during ear infections; "vertigo"]
-
The term for the sum of all inner ear organs:
Otolith
-
When water enters the cavity of an ear, motion sickness can occur. This is called................
Caloric Stimulation
-
This may be an evolved automatic response to poison-like symptoms
Motion sickness
-
This may give a pilot the sensation of gaining altitude during flight if they tilt their head backwards
False climb illusion
-
These nerves extend to the cerebellum, including the medulla, pons, and spinal cord.
Vestibular nerves
-
Causes of this may include: swelling, decreased blood flow, and multiple sclerosis.
Vertigo
-
Possibly caused by a tumor, this is characterized by a ringing in only one ear
Acoustic neuroma
-
These senses include touch, temperature, proprioception (AKA kinesthesia/body position) and pain.
Somatosenses
-
This involves recpetors in the joints, tendons, and muscles. It is a key component in muscle memory and hand-eye coordination. It is a sense of relative position in relation to other body parts.
Kinesthesia
-
When your inner body senses: stomach aches, Dr H's gallbladder , and warm drinks
organ senses
-
pressure, vibrations, heating, cooling, and pain are stimuli for ...
somatosenses
-
This is the largest organ
skin
-
These receptors respond to mechanical stimulation, like a pat on the back
Mechanicoreceptors
-
Mechanical receptor sensitivity is greater where?
farther from the trunk; at the limbs & digits
-
This cortex is more developed in people who use their skin more, like guitarists
somatosensory cortex
-
a sensory receptor that responds to potentially damaging stimuli by sending nerve signals to the spinal cord and brain. (PAIN)
nociceptor
-
a sensory receptor that codes absolute and relative changes in temperature
Thermoreceptor
-
Similar to the other pathways of transduction, Somatosensory's pathway is.... 1. _____ 2. ______ 3. Medulla 4. Thalamus 5. (somatosensory) cortex
1. skin 2. spinal cord
-
When association areas are damaged, it can sever sensation and perception associations. Knowing you are touching something, but not being able to perceive what it is, is called _____________
tactile agnosia
-
can the environment influence pain?
maybe.. note references to soldiers reporting less pain on battlefield and more when returned home/base?
-
Note that inflamation and swelling increases pain sensitivity to help alert and convince a person to not persue further damage
Ok.
-
(between the frontal and temporal lobe) This is considered a limbic related cortex (emotion). If damaged, it can lead to the loss of urges to smoke. (Wikipedia: Henry Gray in Gray's Anatomy is responsible for it being known as the Island of Reil.)
Insula [Insular cortex]
-
connected with the limbic system, this is involved with empathy, emotion, decision making, etc. When you wince seeing someone kicked in the groin.
Anterior Cingulate Cortex (ACC)
-
The sensation of a limb when a limb is not present (amputation)
Phantom limb
-
pain is reduced endogenously by
opioids
-
This chemical is found in spciy/hot foods like a pepper that stimulates the pain sensors
Capsaicin
-
morphine best prevents what kind of pain?
small, dull aches
-
histamines in the skin are in part responsible for this. (morphine and novocain use stimulate this as well)
itching
-
The two chemosenses
Gustation and olfaction
-
Taste is produced by chemicals in the saliva. List the 5 types of taste produced by the tounge:
- Bitter
- Sweet
- Sour
- Salty
- Umami - MSG, meat taste
-
The term used for the bumpy taste buds on the tounge. (there are 10,000 of them).
Papilla(e)
-
The lack of a sense of smell
Anosmia
-
the transduction pathway of gustation--
1._______ 2. medulla 3.Thalamus 4.Primary Gustory Cortex (Frontal cortex) (Insula)
cranial nerves
-
In olfaction, molecular weight produces unique smells. Where are the smell receptor cells that process this kept?
olfactory epithelium
-
The olfactory bulb/system can produce a sense of want/do not want or good/bad based on smell because it is connected to......
the limbic system (emotion control)
-
This structure responds to pheromones in animals(?maybe humans?), like a dog to a fire hydrant.
Vomeronasal organ (VNO)
-
endorphins and other endogenous opioids are this neurotransmitter type:
peptides
-
endocanabinoids etc. are a type of this:
lipids
-
adenosine is a type of :
nucleoside
-
nitric oxide is a ...
soluble gas
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