Which of the following compounds is a sodium salt of glutamic acid?
MSG
Which of the following neurotransmitters is a precursor for serotonin?
Tryptophan
An amino acid that is NON essenestial and associated with heart disease?
Homocysteine
What is the disadvantage of a oral peptide drug?
LOW Bio-availability
Which disease is cx by GLY12--> Val cx enzyme "RAS" to become active
Cancer
Which amino acid would most likely not be present in an ALPHA-helicial structure of protein?
Proline
Properties of Fibrous Proteins
3
SFE
Stiff
Elongated Proteins
Form from insoluble fibers
A prothesthetic group of a protein is a non-protein structure that is
permanently associated with the protein
What step occurs last during the sliding filaments of muscle?
Power Stroke
Pi released from myosin
cx hinge to close
Monoclonal antibodies are those produced by
by a population of identical B cells (a clone) responding to one single epitope of a protein.
This drug is a recombinant, human mouse chimeric monoclonal antibody
binds specifically to the extracellular domain of the human epidermal growth factor receptor(EGFR)
What drug is it
Erbitux (cetuximab)
Which of the following processes requires caspases?
Apoptosis
Phosphatidylcholine is from which class of membrane lipids?
Glycerophospholipids
Which of the following processes ends with a membrane fusion event?
Exocytosis
Macroautophagy
The process by which lysosomes recycle organelles
describes the function of intermediate filaments
Provides tensile strength in the cell
Is cystol an organelle
NO
This receptor is named for its endogenous ligand
Andrenergic receptor
Prodrugs are active or inactive when administred
Inactive
Glutathione and N-acetyl cysteine can be used to treat an acetaminophen overdose because
They both contain a thiol
When induction occurs, what happens
prodrugs and drugs are metabolized more due to drug-drug interactions
Biotransformation does what to the structure of the drug
makes the drug more polar
Why does biotransformation make the structure of the drug more polar
to become more reactive within the body.
Lipitor (Atorvastatin) in a competitive or non-competitve inhibitor of HMG CoAce Reductase