Nitroglycerin

Antianginal Agent

• Relaxes vascular smooth muscle
• Dilating peripheral arteries and veins
• Causes pooling of venus blood, decreasing venous return to the heart, which decreases preload
• Reduces left ventricular systolic wall tension which decreases afterload

• Angina
• Ongoing ischemic chest discomfort
• Hypertention
• Myocardial ischemia associated with cocain intoxicaion

• Headache
• Hypotension
• Bradycardia
• Lightheadedness
• Flushing
• Cardiovascular Collapse
• Methemoglobinemia

• Hypotension
• Severe Bradycardia or Tachycardia
• Increased ICP
• Intracranial Bleeding
• Use of any erectile dysfunction medications

• Anemia
• Closed-Angle Glaucoma
• Hypotension
• Postural Hypotension
• Uncorrected Hypovolemia

1 Tablet (0.3 - 0.4 mg) at 5min intervals to a maximum of 3 doses

1 (0.4mg) spray at 5min intervals to a max of 3

2% topical (Nitro-Bid ointment); Apply 1-2 inches over chest wall, cover with transparent wrap and secure with tape

12.5 - 25mcg

• 5mcg/min
• May increase by 5 to 10mcg/min every 5-10 minutes

• Drop in blood pressure of 10%
• Relief of Chest Pain
• Return of ST segment to normal on a 12 lead ECG

0.25 - 0.5mcg/kg/min

0.5 - 1mcg/kg/min

1 - 3mcg

5mcg/kg/min

• Right Ventricular MI
• Hypotension
• C