Physiology Exam1 (part 2)

/_\E (delta E) =

4 Factors that affect rxn direction & rate

Highest energy state of a molec during a rxn (must be reached in order for rxn to continue)

Concept; high concentrations of product cause shift back & vice versa

Biological catalyst which orients substrates in such a way as to speed up rxn (which decreases activation energy)

Where substrate binds to enzyme, forming an enzyme-substrate complex

Measure of strength of binding b/w substrate and enzyme

Enzymes with the same function but diff structure

CPK (creatinine phosphokinase) is an isoenzyme which has ___ diff isoforms which are found in diff tissues

Ion or molec required by an enzyme to be active; allow substrate to bind to active site which increases affinity

When a modulator molec increases or decreases affinity by changing enzyme's shape or changing it's active site's shape, but doesn't take place AT the active site

2 binding sites of enzymes

When an enzyme (B) attaches modulator to enzyme A covalently to chg enzyme A active site, then enzyme (C) breaks covalent bond that was formed, causing enzyme A to go back to normal
(Method of modulating activity)

When the presence of a product can inhibit an enzyme in a metabolic pathway

Enzyme w/slowest rxn rate in a metabolic pathway