Diabetes Medications 1

What medications are classified as biguanides?

What is metformin's brand name?

What is the HbA1C lowering effect of metformin (glucophage)?

Which medication works by enhancing insulin sensitivity in hepatic and muscular tissue, allowing for increased glucose uptake? (No direct effect on beta-cells)

List the four first generation sulfonylureas (generic and brand) -

List the four second generation sulfonylureas (generic and brand) -

What is the HbA1C lowering effect of the sulfonylureas?

What medication enhances insulin secretion from pancreatic beta cells by binding to a receptor linked to closing a K+ efflux channel, depolarizing the membrane, opening voltage-gated calcium channels and thus causing translocation of insulin granules?

What drugs are classified as meglitinides? (brand and generic)

What is the brand name for nateglinide?

What is the brand name for repaglinide?

What is the brand name for glipizide?

What is the brand name for glyburide?

What is the brand name for micronized glyburide?

What is the brand name for glimiperide?

What is the HbA1C lowering effect of the meglitinides?

What medications work by stimulating insulin secretion from pancreatic beta cells by binding to a site adjacent to the SUR (requiring the presence of glucose for action)?

What drugs are classified as thiazolinediones (TZDs/glitazones)?

What is the brand name for pioglitazone?

What is the brand name for rosiglitazone?

What medications act by binding to peroxisome proliferator-activated receptor (PPAR-gamma), indirectly increasing insulin sensitivity at muscle, liver and fat cells (requires presence of insulin)?

What medications are classified as alpha-glucosidase inhibitors?

What is the HbA1C lowering effect of TZDs?

What is the brand name for acarbose?

What is the brand name for miglitol?

What is the HbA1C lowering effect of the alpha-glucosidase inhibitors?

What medications act by competitively inhibiting intestinal enzymes to delay the breakdown of sucrose and carbohydrates, reducing post-prandial BG rise?

What medications are classified as DPP-IV inhibitors?

What is the brand name of sitagliptin?

What is the brand name of saxagliptin?

What is the HbA1C lowering effect of the DPP-IV inhibitors?

What medications prolong the t1/2 of endogenous GLP, reducing glucagon levels and stimulating glucose dependent insulin secretion (does not alter gastric empyting)?