muscoskeletal extra

MOA: Inhibits bone resorption SE: Patients may experience localized skin reaction to the injection or systemic reaction if allergic to salmon

MOA: Provides calcium for bone formation U: treats post menopausal osteoporosis and prevention of progressive bone loss

SE: Hot flashes Peripheral edema leg cramps/muscle spasm

DI: Take with food or milk Avoid aspirin May cause drowsiness Do not drink alcohol SE: G.I. Upset

Use: Anti-inflammatory, Analgesic, 1st line for gouty arthritis

Use: Anti-Inflammatory & Analgesic ~also marketed as immediate release Potassium Salt (Cataflam)

Uses: Osteoarthritis, Rheumatoid arthritis and Juvenile Rheumatoid arthritis

Considered a Schedule III-V drug Commanders will consider it a locally controlled item

Considered a Schedule III-V drug

Intoxication or poisoning due to an overdose or excessive use of the ergot alkaloids is known as ...........

Use: Abort or prevent vascular headaches (migraines) Controls effectively up to 70% of acute migraine attacks *contraindicated in pregnancy* SE: Vertigo, itching, nausea and vomiting

Migranal is a ____________ DHE45 is a ______________

A new class of anti-migraine agents that work primarily on the serotonin receptor causing cerebral vasoconstriction

MOA: Reduces the production of uric acid

MOA: Increases urinary excretion of uric acid

What does DMARD stand for?

Agents that completely block nerve impulses to skeletal muscles causing complete skeletal muscle relaxation

Agents cause complete blocking of nerve impulses so most pharmacists do not strictly consider them skeletal muscle relaxants

When nerve impulses that stimulate skeletal muslce tone become blocked at the spinal cord and results in diminished skeletal muscle tone

Three major categories of skeletal muscle relaxants

The onset of blockade is usually rapid as motor weakness gives way to

What 2 drugs are short acting NMBs with an onset of ~1 minute and a duration of action less than 30 minutes?

An acetylcholinesterase inhibitor used to antagonize or reverse the action of these agents

MOA: acts like an excess of acetylcholine at NM junction to depolarize the muscle receptor site and prevent its repolarization-causes an initial muscle contraction

Use: ultra-short acting neuromuscular blocking agent used as an adjunct to anesthesia or for rapid sequence intubation (short procedures Is the only depolarizing agent approved for use in the U.S.

Use: Muscle spasticity and rigidity associated with multiple sclerosis or cerebral palsy, also spinal cord injuries SE: Frequent urination

MOA: Reduces skeletal muscle tone through a direct effect on contraction.