Pharmacology

as desired/directed

when needed/necessary

before meals

twice a day

capsule

drop

hour

intravenous

intramuscular

number

by mouth

every 4 hours even

every 6 hours even

every 8 hours even

every 12 hours

take

immediately/with in 5 minutes

afternoon

tablet

three time a day

four times a day

every 2 hours

after meals/eating

half life

length of time required for plsma concentration of a med. to decrease by 1/2 after administration

Right Patient, Right Med., Right dose, Right Route, Right Time, and Right Documentation

• 1. Preclinical investigation
• 2. Clinical investigation
• 3. Review of New Drug App. (NDA)
• 4. Postmarketing Surveillance

designed to dissolve in alkaline environment of sm. intestine (can NOT be crushed b/c meds would be exposed directly to stomach acid)

• XR, LA, SR
• can NOT be crushed

study of how the body responds to drugs

study of how drugs are handled in the body

what the drug benefits/helps (ex. anti-hypertensive)/ the WHAT

• organizing drugs on basis of their mechanism of action (ex. vasodialator)/
• the HOW

drug/agent that causes developmental birth defects

taking of multiple drugs concurrently

• higher adipose tissue
• amount of unbound drug rises/amount of drug available to produce an effect increases too
• Half-life may increase as much as 40%