Aminoglycosides

Aminoglycosides kill the ________ cell by affecting ______ _______.

Aminoglycosides are effective against ______ gram-______ infections.

Aminoglycosides are used to sterilize ____ prior to surgery.

Aminoglycosides are used to destroy _____-producing bacteria to prevent absorption of _______ in hepatic ___________.

Aminoglycosides are used in infections caused by:

When dealing with Aminoglycosides some common meds are:

_______ is the prototype for aminoglycosides antibiotic.

___ route is the preferred for optimal distribution to tissue, but may be use ___.

When dealing with aminoglycoside oral route is _____ absorbed so effective orally only to cleanse ____ prior to surgery to eliminate bacteria in ____ or to prevent absorption of _______ in hepatic encephalopathy.

What other 2 routes can be used b/c of poor penetration of CSF by other routes?

When dealing with aminoglycosides a contraindication is if the pt has preexisting ____ disease, _________ _____, and _______ and ______ (use cautiously)

Contraindications for aminoglycosides are concurrent orders for renal toxic agents such as: (list 3)

When dealing with significant drug interactions, Aminoglycosides may be microbiologically inactivated with concurrently high concentrations of ________ greater than ____mcg/mL.

When dealing with aminoglycosides do not mix other __________ in the same ___ fluid.

With oral anticoagulant therapy, bleeding may increase b/c aminoglycosides decrease Vitamin __ synthesis in the _______ tract.

When dealing with significant drug interactions of aminoglycosides, concurrent administration of __________ (_______) may mask signs of toxicity.

What lab studie determine that toxic levels do not occur?

what lab studie assures that theraputic levels of drug are maintained b/t doses?

____ _____ _____ ( ) is used to monitor effectiveness of drug therapy.

_______ and immature neutrophils, called ____ or ____, are increased in acute bacterial infections.

Neutrophils and lymphocytes make up ___% to ___% of leukocytes; when one part of the differential increases, as in response to an acute infection, another part has to decrease; a "____ to the___" signifies an increase in neutrophils and, therefore, an acute bacterial infection.

What 2 lab studies monitor renal function?

Out of creatinine and BUN test which one is most specific test for renal function?

If creatinine level rises 3 to 4 days into treatment what does that indicate?

List 4 side effects for aminoglycosides:

When dealing with aminoglycoside's adverse effects/toxicity, __________ and __________ are two common toxicities associated with therapy with aminoglycosides and occurs when _____ levels are elevated.

Neuromuscular blockade: secondary to inhibition of _________ release; may be seen in clients with _________ _____ or clients receiving neuromuscular blocking agents as ________ _____ (_____) or __________ (________); use ______ salts to reverse the blockade.

________ is known as a secondary infection caused by eradication of normal flora.

List 2 superinfections:

Candidiasis is a secondary infection usually of ___ and ____ _______ caused by ______ _____.

Candidiasis is often associated with __________.

Pseudomembranous colitis is a secondary infection of the ____ usually caused by ________ ______.

Normal creatine levels are?
Normal BUN levels are?

Take oral ________ on an empty stomach, __ to __ hours before any meal or other drugs.

When administring a med you need to know: