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What parts make up the CNS?
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What parts make up the PNS
- Cranial Nerves
- Spinal Nerves
- Enteric NS
- Sensory Receptors
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Where are Purkinje cells located?
Cerebellum
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Where are pyramidal cells located?
Cerebral Cortex
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How many pairs of cranial nerves?
12
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How many pairs of spinal nerves?
31
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What are the 4 glial cells? CNS
- Astrocytes
- Oligodendrocytes
- Microglia
- Ependymal
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Astrocytes help how?
Restricts movement of substances through blood brain barrier
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Oligodendrocytes help how?
Myelination in the CNS
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Microglia help how?
Brain macrophages, clean up debris
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Ependymal cells help how?
Make CSF
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What are the 2 glial cells? PNS
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Schwann cells do what?
Myelinate as one axon in segments in internodes
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Satelite cells do what?
Support and nourish the cells in the ganglia
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Neuroglia facts.
- Not electrically excitable
- Make up half the volume of the NS
- Can multiply and Divide
- 6 kinds (4 CNS, 2 PNS)
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Hyperpolarizing and Depolarizing
- Sodium going in = hyperpolarizing (IPSP)
- Potassium going in = depolarizing (EPSP)
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Nodes of Ranvier
Where no myelin is present and makes AP jump from one node to the next
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Factors that effect propogation in AP?
- Axon diameter
- Amount of myelination
- Temperature
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Electrical Synapse
Gap junctions allow cells to connect and transfer information to synchronize the activity of a group of cells
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Chemical Synapse
One way transfer of information from a presynaptic neuron to a postsynaptic neuron
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Can mature neurons replicate?
No
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Where is anesthesia given?
In the epidural space
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Can the brain modulate spinal reflexes?
Yes
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What is propioception?
The unconscious perception of movement and spatial orientation
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What is ducussation?
Crossing over
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What is spatial summation?
Releasing all at once to generate an AP
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What is temporal summation?
Releasing each bulb to increase frequency which eventually add up to generate an AP
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AP vs GP
- AP=voltage gated, 100mv, refractory period
- GP=ligand gated, 1-50mv, no refractory
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Removal of Neurotransmitter
- Diffusion
- Enzymatic degradation
- Uptake into cell
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Repair of PNS
- Chromatolysis
- Wallerian degeneration
- Formation of a regeneration tube
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Repair in CNS
- Not possible
- Rapid formation of scar tissue
- Inhibitory influences from neruglia
- Absence of growth stimulating cures
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Plasticity
The capability to change based on experience
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Meninges in order from deepest to farthest out?
- Pia Mater
- Arachnoid Mater
- Dura Mater
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Cauda equina
Roots from the spinal cord, near the end of the spinal cord, reaching down to sacrum
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Nerves in Spinal Nerves
- Cranial Nerves-8
- Thoracic Nerves-12
- Lumbar Nerves-5
- Sacral Nerves-5
- Coccygeal Nerves-1
- Medulla oblongata
- Dermatomes
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Dermatomes
Certain segments of skin that are supplied by spinal nerves that carry somatic sensory nerve impulses to the brain
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Spinal nerves have what covering them?
- Connective tissue
- Endoneurium
- Perineurium
- Epineurium
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Cervical Plexus Important Nerves? (Deep Branches)
- Phrenic-Diaphragm
- Ansa Cervicalis-Divides into superior and inferior roots
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Cervical Plexus Roots?
C1-C4
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Brachial Plexus Roots?
C5-T1
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Lumbar Plexus Roots?
L1-L4
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Sacral Plexus Roots?
L4-S4
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Brachial Plexus Branches #1
Musculocutaneous-Coracobrachialis, biceps brachii, and brachialis muscles.
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Brachial Plexus Branches #2
Axillary-Deltoid and teres minor muscles; skin over deltoid and superior posterior aspect of arm.
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Brachial Plexus Branches #3
Radial-Triceps brachii, anconeus, and extensor muscles of forearm; skin of posterior arm and forearm, lateral two-thirds of dorsum of hand, and fingers over proximal and middle phalanges.
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Brachial Plexus Branches #4
Median-Flexors of forearm, except flexor carpi ulnaris; ulnar half of flexor digitorum profundus, and some muscles of hand (lateral palm); skin of lateral two-thirds of palm of hand and fingers.
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Brachial Plexus Branches #5
Flexor carpi ulnaris, ulnar half of flexor digitorum profundus, and most muscles of hand; skin of medial side of hand, little finger, and medial half of ring finger.
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Lumbar Branches #1
Femoral-Largest nerve arising from lumbar plexus; distributed to flexor muscles of hip joint and extensor muscles of knee joint, skin over anterior and medial aspect of thigh and medial side of leg and foot.
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Lumbar Branches #2
Obturator-Adductor muscles of hip joint; skin over medial aspect of thigh.
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Sacral Main Nerve
Sciatic-Actually two nerves—tibial and common fibular—bound together by common sheath of connective tissue; splits into its two divisions, usually at the knee. As sciatic nerve descends through thigh, it sends branches to hamstring muscles and adductor magnus.
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Sacral Side Nerves #1
Tibial-Gastrocnemius, plantaris, soleus, popliteus, tibialis posterior, flexor digitorum longus, and flexor hallucis longus muscles. Branches of tibial nerve in foot are medial plantar nerve and lateral plantar nerve.
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Sacral Side Nerves #2
Common fibular-Divides into superficial fibular and deep fibular branch.
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Branches of Tibial Nerve #1
Medial Plantar-Abductor hallucis, flexor digitorum brevis, and flexor hallucis brevis muscles; skin over medial two-thirds of plantar surface of foot.
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Branches of Tibial Nerve #2
Lateral Plantar-Remaining muscles of foot not supplied by medial plantar nerve; skin over lateral third of plantar surface of foot
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Branches of Common fibular #1
Superficial fibular-Fibularis longus and fibularis brevis muscles; skin over distal third of anterior aspect of leg and dorsum of foot.
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Branches of Common fibular #2
Deep fibular-Tibialis anterior, extensor hallucis longus, fibularis tertius, and extensor digitorum longus and extensor digitorum brevis muscles; skin on adjacent sides of great and second toes.
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Sacral Plexus other Nerve
Pudendal-Muscles of perineum; skin of penis and scrotum in male and clitoris, labia majora, labia minora, and vagina in female.
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Spinothelamic
Regulates? temperature, pain, taste, and tickle
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Reciprocal Innervation
Simultaneously cause contraction of one muscle and relaxation of its antagonists
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Monoplegia
Paralysis of one limb
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Diplegia
Paralysis of both upper limbs or both lower limbs
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Paraplegia
Paralysis of both lower limbs
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Hemiplegia
Paralysis of the upper limb, trunk, and lower limb on one side of the body
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Quadriplegia
Paralysis of all four limbs
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Interneurons
Or association neurons are located in the CNS and are multipolar in structure
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