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Dose of drugs
- Pethidine + Phenargan - 50mg+25mg IM sos
- Ketorolac 30mg IV tds
- Calcium dobesilate for varicose vein
- Tab cefadroxil 500mg BD
- Inj Phenytoin 100mg TDS
- Tab Cotrim DS 1 tab po BD
- Inj Octreotide 100micro gram sc TDS
- 10% calcium gluconate, 10ml over 10 minutes
- Inj UFH 5000 IU SC BD
- Tab Strocit (Citicholine) 500mg PO BD
- Tab Stemetil (Prochloroperazone) 5mg IV sos
- Inj Rallidex NS (Dextran 40) - for hypovolemic shock/ septic shock/severe burns
- Seranace - haloperidol
- Laxopeg - laxative + PEG
- Inj Granisatron 1mg IV OD
Inj MgSO4, 1gm in 100ml NS IV over 4 hours
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Pain management
- Tab TRD contin 1 tab PO BD
- Morphine 3mg TDS
- Durogesic (Fentanyl transdermal patch) Local application for pain management
- Syp Mor 5ml (2mg/ml) SOS
- Tab Morcontin 10mg PO sos
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Supportive medicines and total parenteral nutrition
- Pentasure + Soyaprotein 2tsf each in a glass of milk TDS
- Triptene buscits 2piece BD
- Inj Alanine I unit IV BD
- Inj Celemin (amino acids + sorbitol) I pint IV BD
- Inj Celepid (intravenous fat) I pint IV OD
- Inj Oliclinomol 1 litres IV over 16 hours and 8 hours gap
Use 10% dextrose in between the TPN to prevent hypoglycemia. TPN is given for 16 hours, and then 10% dextrose in eight hours
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Urinary system
Tab flavoxate 200mg PO TDS - anticholinergic, indicated for symptomatic relief of interstitial cystitis, dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis
Oxyspas (Oxybutynin) 2.5/5mg - anticholinergic- to treat overactive bladder
Tab Urimax (Tamsulosin) 0.4mg PO HS - alpha 1 adrenergic blocker
Tab Alfuzosin 10mg PO OD - alpha 1 adrenergic blocker
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GI system drugs
Itopride (Ganaton, Gantoon) 50mg PO TDS. It is a prokinetic benzamide derivative unlike metoclopramide or domperidone. It is used in dyspepsia of a non-ulcer/dysmotility type (gastric "fullness", discomfort, and possible pain), delayed gastric emptying and anorexia
For ulcerative colitis
Mesacol (Meselamine) 400mg PO TDS - 1 hr before food or 2 hours after food
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Respiratory system drugs
- Seroflo rotacap - Contain salmeterol + Fluticasone
- Tiova - Tiotropium
- Nacfil (N acetylcysteine) 600mg PO tds as mucolytic agent
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Cardiovascular system
- Inj Amiodarone 900mg in 500ml NS over 24 hours. (amiodarone in 150mg/3ml injection)
- Amiodarone
- - 1ml = 50mg, 1ampoule = 150mg
- - How to prepare - 7ampoules (1050mg in 50ml (21ml drug + 29ml 5% dextrose)
- - Bolus dose - 150mg over 10 minutes jQuery110101646906235989285_1485174722241jQuery110104313412200343545_1498016749827?
GTN 30microgram/kg/min
Labetalol - bolus 2.5mg IV stat
Tab Diazepam (NOTEN) 2mg PO BD
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Endocrine system
Zoledronic acid 5mg/100ml IV infusion - is a biphosphonate used in Bone complications of cancer, osteoporosis and paget's disease
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Neuro drugs
- Tab Pregabalin 75mg PO BD
- Diamox (acetazolamide) 250mg TDS
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Immunosupresents -
- Immunosupressents in Renal Transplant
- - Tab Pangraf (tacrolimus) 2.5mg PO BD
- - Tab Mycofit (Mycophenolate) 1gm PO BD
- - Tab Cortilone 20mg PO OD
Anti-thymocyte globulin (ATG) 60mg in 500ml of NS - is an infusion of horse or rabbit-derived antibodies against human T cells, which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia.
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Blood disease
Neupogen (filgrastim) 0.5ml sc stat - is a granulocyte colony-stimulating factor (G-CSF) analog, used to stimulate the proliferation and differentiation ofgranulocytes
Acitrom (Acenocoumarol) 2mg
Enoxaparin (LMWX) 60mg SC
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ATT drugs dose
HRZES 5, 10, 25, 15, 15 mg/kg/day
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Triple drug regimen in IV
- Inj Pantocid 40mg IV BD
- Inj Clavum 1.2gm IV BD
- Inj Levoflox 500mg IV BD
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Oral hypoglycemic drugs
Tab Glycazide 5mg PO BD continue (for mild renal failure, upto grade III CKD)
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Insulin
- Fast acting
- - regular insuin (Huminsulin, Soluble insulin, actrapid)
- - insulin lispro (Humalog)
- - Insulin aspart (Novorapid)
Intermediate acting - NPH (Isophane, Insulatard)
- Long acting
- - Glargine (Lantus) -
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What is Mixtard?
- Mixtard contains both fast-acting (soluble) and long-acting (isophane) insulin:
- Mixtard 30: soluble insulin 30% and isophane insulin 70%;
- Mixtard 40: soluble insulin 40% and isophane insulin 60%;
- Mixtard 50: soluble insulin 50% and isophane insulin 50%.
- Novomix 30 -
- - Soluble insulin aspart (rapidly-acting insulin, within 10 to 20 minutes)
- - Protamine-crystallised insulin aspart (intermediate-acting insulin) - It takes longer to act, but its effects last much longer.
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Cardiovascular system
Tab TGR (Fenofibrate) 160mg OD for 3 months - to reduce cholesterol and triglyceride
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Renal system drugs
- Desmopressin (Minirin) 2 puff stat and repeat
- Inj Vasopressin 2U s/c stat
If Urine output is >1000ml/hr, 500ml in two consecutive hour or >300ml in three consecutive hours
Tab Fludrocortisone 200mg PO BD
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What is nupogen?
Neupogen is used to stimulate the production of granulocytes (a type of white blood cell) in patients undergoing therapy that will cause low white blood cell counts
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Broad spectrum coverage
- Inj Tazopip 4.5 gm iv TDS
- Inj Clindamycin 600mg iv TDS
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What to look for patients on anticoagulants
- New spots of bleeding
- Intracranial bleeding leading to hypertension
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GIK
10U regular insulin with 10mEq/L potassium in 500ml of 10% dextrose at 100ml/hr
- Uses in
- - Myocardial infarction
- - Septic shock
-
Drug of choice for any bite
Amoxyclave
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Antibiotics
- Cell wall inhibitors
- - Inj Imipenam 500mg +Cilastatin 500mg - 1gm IV TDS or QID (Not more than 4gm/day and >1.5gm/dose)
- Inj Meropenam 1gm IV in 100ml of NS BD
- Vancomycin (500mg in a vial) - 10 mg/kg per dose given every six hours, concentrations of no more than 5 mg/mL and rates of no more than 10 mg/min are recommended in adults.
- Inj Acyclovir 800mg IV TDS
- - Inj Teicoplanin (Targocid) 400mg IV stat followed by 200mg IV OD. Teicoplanin is
- Protein synthesis inhibitor
- - Inj Clindamycin 600mg IV tds
- - Inj Streptomycin 750mg IM OD
- Nucleic acid synthesis inhibitor
- - Levofloxacin 750mg OD for hospital acquired pneumonia
- Tigecycline and Polymyxin B most strongest antibiotics, very expensive. Polymyxin B is an antibiotic primarily used for resistant Gram-negative infections
- Polymyxin B 5 lakhs units diluted in 500ml of 5% dextrose over 1-1.5 hours BD
- Inj Tigecycline 100mg IV stat followed by 50mg IV BD
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What is Teicoplanin?
- Teicoplanin owns a molecular structure which is related to that of vancomycin with similar spectrum of activity. Its mechanism of action is to inhibit peptidoglycan polymerization.
- Due to its reduced rate of side effects that does not require close monitoring, its longer serum half-life and a simplified mode or application, teicoplanin is a valuable alternative of Vancomycin and has become the glycopeplide or choice in many hospitals.
-
What is tigecycline?
This antibiotic is the first clinically available drug in a new class of antibiotics called the glycylcyclines. It is structurally similar to the tetracyclines.
- Tigecycline is active against
- - Gram-positive bacteria
- - Gram-negative bacteria
- - Anaerobes
- - Methicillin-resistant Staphylococcus aureus (MRSA)
It has no activity against Pseudomonas spp. or Proteus spp.
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Alcohol withdrawal
Tab Chlorodiazepoxide 15mg PO BD
-
Trade names
- Magnex Forte - Sulbactam and cefoperazone
- Cilanem - Imipenam + Cilasten
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Tazobactam
Decreases platelets
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Immunosupressant drugs
- Tab Tacrolimus 1mg po BD
- Tab Mycophenolate 500mg PO BD
-
Different drugs available at
Cholestyramine sachet in Norvik hospital
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Vitamins
Thiamine
Riboflavin - 25, 50mg
Pyridoxine - 10mg tablet
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Unit and Pint
- Unit - 350 ml
- Pint - 500 ml
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Pleurodesis
Oxytetracycline (50mg/ml) - 20ml of Oxytetracycline (1gm) in 70ml of NS with 10ml of xylocaine, tetracycline is irritant, so needs lignocaine
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Bicarbonate replacement
Number of ampules = (0.3 X base deficit X weight)/9
-
Ionotropes dose
- Dopamine and Dobutamine
- - Dopamine - 1ampule - 200mg
- - Dobutamine - 1ampule - 250mg
- - preparation - body weight X 3 mg in NS/D5
- - ml/hr = mcg/kg/min
- - Dose - 5-20mch/kg/min
- Noradrenaline/Adrenaline
- - Noradrenaline - 1ampule - 4mg
- - Preparation - 4mg in 50ml of NS/D5
- - Dose - 0.01-0.3 mcg/kg/min
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Goals of resiscutitation
- SBP > 90mmHg
- MAP >65 mmHg
- CVP 8-12 mmHg (12-15 mmHg in mechanically ventilated patients)
- Urine output - >0.5ml/kg/hr
- ScVO2 >70%
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Doses of vasopressors
- Escalate every 5 minutes
- Descelate every 30 minutes
- Dopamine and dobutamine
- - Preparation - body weight X 3 mg in 50ml NS/D5W
- - ml/hr = mcg/kg/min
- - Dose - 5-20 mcg/kg/min
- - Route - peripheral/central line
- Noradranaline and adrenaline
- - Preparation - 4mg in 50ml NS/D5W or 8mg in 100ml NS/D5W
- - Dose - 0.01-0.3 mcg/kg/min
- - Route - central line
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Hemorrhoids d
Protek oinment - Lidocaine, Hydrocortisone, Zinc oxide and allantoin
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